Publications by authors named "Takashi Aritsu"
Article Synopsis
- Researchers studied the immune response in 109 patients with plasma cell dyscrasia (PCD) after receiving two or three doses of the SARS-CoV-2 mRNA vaccine, focusing on the production of antibodies and immune cells.
- The results indicated that while ongoing anti-myeloma treatments negatively affected antibody production, booster dose (Dose 3) significantly improved antibody levels and the number of patients achieving adequate immune response.
- The study underscored the importance of the booster vaccine for enhancing both humoral (antibody) and cellular immune responses in PCD patients, noting specific drug classes that had varying impacts on vaccine effectiveness.
Article Synopsis
- This study evaluated the immune response to SARS-CoV-2 mRNA vaccines in 165 lymphoma patients, focusing on their antibody levels after the second and third doses.
- Results showed that after the second dose, 56% had adequate antibody responses, while 28% were non-responders, influenced by factors like timing of vaccination after chemotherapy and lymphocyte count.
- After the third dose, there was a notable increase in antibody levels, with 26% of previous non-responders achieving seroconversion, indicating that additional vaccine doses can improve immune responses in immunocompromised individuals.
Article Synopsis
- Chronic hypersensitivity pneumonitis (HP) with fibrosis has a clinical progression similar to idiopathic pulmonary fibrosis (IPF), and research is focused on identifying biomarkers to predict lung function deterioration.
- A study analyzed various factors in chronic bird-related HP, including patient characteristics, serum markers, lung function, and HRCT findings, to understand their relationships with lung function decline.
- Results showed that higher serum levels of CCL17 and lower levels of CXCL9 were significant predictors of vital capacity decline, indicating that these chemokines may help assess worsening lung function in patients.
