Publications by authors named "Takashi Abe"

In remote areas, visiting a laboratory for sleep testing is inconvenient. We, therefore, developed a Mobile Sleep Lab in a bus powered by fuel cells with two sleep measurement chambers. As the environment in the bus could affect sleep, we examined whether sleep testing in the Mobile Sleep Lab was as feasible as in a conventional sleep laboratory (Human Sleep Lab).

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  • The study examined the types of bacteria found on finger skin before and after cleaning with ethanol, and compared them to the bacteria on smartphone touchscreens.
  • The results showed that the bacteria levels on smartphones were low, similar to the levels found on fingers after they were disinfected with ethanol.
  • Ethanol disinfection significantly decreased the number of bacteria on the fingers, reducing it to about 1/13 of the original amount.
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Objective: Whether or not an athlete plays with sports equipment in their hands may influence handgrip strength (HGS) changes during development, but longitudinal studies have not confirmed this. This study compared one-year HGS changes between two sports types (soccer vs. kendo) in children and adolescent athletes.

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Fibrous dysplasia (FD) is a rare skeletal disorder characterized by the replacement of normal bone with fibrous connective tissue, leading to abnormal bone formation. This case report details the successful treatment of a 61-year-old woman with FD at the craniovertebral junction (CVJ). The patient, who had a history of intracranial meningioma and had already been diagnosed with FD, experienced worsening gait disturbance and muscle weakness following a fall.

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Binaural beats can entrain neural oscillations and modulate behavioral states. However, the effect of binaural beats, particularly those with slow frequencies (< 1 Hz), on sleep remains poorly understood. We hypothesized that 0.

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  • The study aimed to analyze the ischemic penumbra and prognosis in patients with acute cerebral infarction using multi-delay pseudo-continuous arterial spin-labeling (pCASL) imaging data, focusing on cerebral blood flow (CBF) and delay time (DT).
  • The participant group consisted of 25 patients treated for cerebral infarction, with evaluations including CBF, DT, infarct sizes, and clinical outcomes through NIHSS scores, alongside treatment variations such as tPA and thrombectomy.
  • Results indicated a significant relationship between CBF and infarct size and NIHSS scores, with DT at the penumbra identified as the most reliable predictor of infarct enlargement, particularly in patients who did not achieve recanalization
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  • Blood eosinophil count is a significant biomarker for managing chronic obstructive pulmonary disease (COPD), but its precise role in the disease still needs further exploration.
  • A study with 93 COPD patients showed that 19.3% had eosinophilic COPD, and while eosinophil counts correlated with some blood parameters, they also indicated lung structural changes related to the disease.
  • The findings suggest that elevated eosinophils may contribute to alveolar damage and thickening of airway walls in COPD patients lacking asthma, highlighting the need for further research on this inflammation type in COPD.
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  • - In-home automated scoring systems for sleep stages are in high demand but face challenges in clinical settings due to issues with electrode contact and limited measurable signals, leading to inaccurate scores.
  • - A new method using an ensemble of small scoring models that utilize different input signal sets can significantly improve scoring accuracy and reduce the impact of electrode contact problems, showing an 8.3 point improvement in accuracy for problematic signals.
  • - This approach not only enhances overall scoring accuracy but also effectively addresses the limitations of traditional methods, making in-home sleep scoring systems more viable for clinical use.
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Objectives: Males, on average, are bigger and stronger than females. Hormonal differences during puberty are one reason given for this performance advantage. However, not all evidence supports that thesis.

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We present a new approach to classifying the sleep stage that incorporates a computationally inexpensive method based on permutations for channel selection and takes advantage of deep learning power, specifically the gated recurrent unit (GRU) model, along with other deep learning methods. By systematically permuting the electroencephalographic (EEG) channels, different combinations of EEG channels are evaluated to identify the most informative subset for the classification of the 5-class sleep stage. For analysis, we used an EEG dataset that was collected at the International Institute for Integrative Sleep Medicine (WPI-IIIS) at the University of Tsukuba in Japan.

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To explore the potential storage and safety of drinking leftover bottled tea beverages from various manufacturers after direct drinking from bottles, we conducted a screening experiment on the growth of salivary bacteria in plastic bottles of tea. The diluted saliva samples from 10 participants were inoculated into the test bottled beverages, which resulted in bacteria, particularly former members of the genus Lactobacillus, growing in some green tea beverages with a neutral pH. In contrast, tea beverages with less bacterial growth contained Streptococcus spp.

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  • The study evaluated a new antigen rapid diagnostic test (Ag-RDT) called Panbio™ COVID-19/Flu A&B, which can detect both SARS-CoV-2 and influenza A/B simultaneously.
  • The test was validated using samples from 235 patients showing respiratory symptoms, with results showing high accuracy against the Omicron variant (sensitivity of 94.8% and specificity of 100%).
  • Additionally, the test demonstrated strong performance for identifying influenza A, with positive and negative predictive values of 98.5% and 98.1%, indicating its effectiveness in clinical settings.
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Non-canonical terpene synthases (TPSs) with primary sequences that are unrecognizable as canonical TPSs have evaded detection by conventional genome mining. This study aimed to prove that novel non-canonical TPSs can be efficiently discovered from proteins, hidden in genome databases, predicted to have 3D structures similar to those of class I TPSs. Six types of non-canonical TPS candidates were detected using this search strategy from 268 genome sequences from actinomycetes.

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Handgrip strength as a biomarker is being studied as a factor in predicting disease onset. However, the effect of improving handgrip strength through physical exercises, such as sports during the developmental period, on disease prevention has yet to be fully elucidated. The Juntendo Fitness Plus (J-Fit Plus) Study is a unique database of anthropometric and physical fitness measurements with over 50 years of accumulated data.

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Anadromous Pacific salmon (genus Oncorhynchus) are known for homing behavior to their natal rivers based on olfactory imprinted memories during seaward migration. The SNARE complex is a regulator of vesicle exocytosis from the presynaptic membrane. Our previous study suggested that its component genes (Snap25, Stx1, and Vamp2) are more highly expressed in the olfactory nervous system (ONS) during the migration stages associated with olfactory imprinting in the evolutionary species of Pacific salmon, such as chum (O.

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Objective: This study aimed to compare the current handgrip strength (HGS) of Kendo athletes with their HGS when they were in university (up to 50 years).

Methods: Eighty male graduates who were Kendo club members during their university days performed anthropometric and HGS measurements, and these HGS were compared with those measured during their university days (mean age of 19.5 years old).

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Background: In recent years, molecular findings on spinal gliomas have become increasingly important. This study aimed to investigate the role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) in the diagnosis of spinal glioma.

Methods: This study included patients diagnosed with spinal cord glioma who underwent 18F-FDG-PET examination at the Department of Neurosurgery, Nagoya University Hospital between January 2016 and November 2023.

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Diabetes mellitus (DM) is caused by insufficient insulin release from the pancreatic β-cells (Type1 DM) and insulin sensitivity in muscles, liver, and adipose tissues (Type2 DM). Insulin injection treats DM patients but leads to hypoglycemia as a side effect. Cortisol and catecholamines are released to activate glucose production from the liver to recover hypoglycemia, called counter-regulatory responses (CRR).

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Spinal cord injury (SCI) induces devastating permanent deficits. Recently, cell transplantation therapy has become a notable treatment for SCI. Although stem cells from human exfoliated deciduous teeth (SHED) are an attractive therapy, their precise mechanism of action remains to be elucidated.

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Objective: Handgrip strength may differ depending on the type of sport played during the developmental period. Youth sports in which athletes hold equipment in their hands may be the most effective for improving handgrip strength. This study aimed to examine the age at which differences in handgrip strength appear by comparing sports that involve gripping (kendo) with those that do not involve gripping (soccer) in young athletes.

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Since the early phase of the coronavirus disease 2019 (COVID-19) pandemic, a number of research institutes have been sequencing and sharing high-quality severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes to trace the route of infection in Japan. To provide insight into the spread of COVID-19, we developed a web platform named SARS-CoV-2 HaploGraph to visualize the emergence timing and geographical transmission of SARS-CoV-2 haplotypes. Using data from the GISAID EpiCoV database as of June 4, 2022, we created a haplotype naming system by determining the ancestral haplotype for each epidemic wave and showed prefecture- or region-specific haplotypes in each of four waves in Japan.

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In the present prospective case series study, we investigated the lesion-detection ability of an AI-equipped colonoscopy as an addition to colonoscopy (CS) screening. Participants were 100 patients aged ≥20 years who had not undergone CS at the study site in the last 3 years and passed the exclusion criteria. CS procedures were conducted using conventional white light imaging and computer-aided detection (CADe).

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Free play in kindergarten can be roughly divided into fine and gross motor activities, but the effects of these activities on improving handgrip strength are unknown. Therefore, we aimed to compare one-year changes in handgrip strength and forearm flexor muscle size in children separated by preferred play in a kindergarten. One hundred and eleven children were recruited from a local kindergarten.

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Objectives: (1) To examine the muscle thickness of various muscle groups of the body to estimate the absolute and relative skeletal muscle mass (SM) in competitive physique-based athletes (Bodybuilding, 212 Bodybuilding, Bikini, and Physique divisions) and (2) to compare values across various divisions of competition and to resistance trained and non-resistance trained individuals.

Methods: Eight competitive physique-based athletes (2 M and 6 F), two recreationally resistance trained (1 M and 1 F) and two non-resistance trained (1 M and 1 F) participants had muscle thickness measured by ultrasound at nine sites on the anterior and posterior aspects of the body. SM was estimated from an ultrasound-derived prediction equation and SM index was used to adjust for the influence of standing height (i.

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