Publications by authors named "Takao Kitanaka"
Article Synopsis
- Drug-induced liver injury (DILI) from 5-aminosalicylic acid (5-ASA) is a rare but serious condition, as illustrated by a case of a 58-year-old woman with ulcerative colitis who experienced severe liver enzyme elevation after starting treatment.
- Diagnostic tests, including blood tests and a liver biopsy, indicated acute lobular hepatitis and raised concerns about autoimmune hepatitis, leading to the discontinuation of 5-ASA.
- The patient's liver function improved with treatment, stressing the need for careful monitoring of liver health in individuals undergoing 5-ASA therapy.
Article Synopsis
- The study investigates the impact of antithrombotic drugs (ATs) on fecal immunochemical test (FIT) results for colorectal cancer (CRC) screening, comparing results between AT users and nonusers.
- Findings indicate that patients on ATs had lower adenoma detection rates (ADRs) and polyp detection rates (PDRs), though the overall predictive value for detecting invasive CRC remained similar.
- Notably, the use of warfarin was identified as a potential positive predictive factor for invasive CRC detection among AT users, suggesting it might have some influence on FIT outcomes.
Background And Aim: Oxaliplatin can lead to hepatic sinusoidal injury, called hepatic sinusoidal obstruction syndrome (SOS), resulting in portal hypertension-related complications. This could worsen the clinical course of the patients treated with oxaliplatin. Early diagnosis is challenging.
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