Intra-vitreal gas injection and supine positioning for hypotony post-intrascleral intraocular lens fixation.

Purpose: This study aimed to report a case of intravitreal gas injection in the supine position for hypotony after intrascleral intraocular lens (IOL) fixation in a patient with Vogt-Koyanagi-Harada (VKH) disease.

Observations: A 72-year-old Japanese female patient presented with blurred vision in her right eye. Both eyes exhibited a sunset glow fundus due to VKH disease.

Comparison of Surgical Outcomes Between Ab Interno Suture Trabeculotomy and Ab Externo Metal Trabeculotomy in Adult Patients with Glaucoma.

Purpose: To compare the outcomes of ab interno suture trabeculotomy (AbI-TLO) and ab externo metal trabeculotomy (AbE-TLO) in adult patients with glaucoma aged over 40 years.

Patients And Methods: A retrospective chart review was conducted, including adult patients with glaucoma who underwent AbI-TLO or AbE-TLO between January 2015 and June 2019. A single surgeon (YO) performed all the operations.

Subarachnoid hemorrhage-negative Terson syndrome after intracranial artery treatment with a flow diverter device.

Purpose: To report a case of subarachnoid hemorrhage-negative Terson syndrome following intracranial artery treatment with flow diverter stents.

Observations: A 40-year-old Asian woman presented with floaters in her right eye after treatment of an intracranial aneurysm with flow diverter stents. Vitreous hemorrhage and sub-inner limiting membrane (sub-ILM) hemorrhage were present in her right eye.

Synthesis, Structures, and Properties of Neutral and Radical Cationic S,C,C-Bridged Triphenylamines.

A structurally constrained S,C,C-bridged triphenylamine was synthesized, and the corresponding radical cation was obtained as a hexachloroantimonate by chemical oxidation. An X-ray crystallographic analysis revealed an almost planar structure for this radical cation, which thus represents the first example of a planar, -unsubstituted triphenylamine radical cation analogue with a sulfur bridge. The electronic properties of the radical cation were examined by UV-vis-NIR and ESR spectroscopy as well as DFT calculations.

Perturbation effect of parallel-plate ionization chambers on buildup dose measurements in transverse magnetic fields.

The aim of this study is to investigate the perturbation effect of parallel-plate ionization chambers on the buildup dose measurement in transverse magnetic fields, using Monte Carlo (MC) simulation. The NACP-02 and ROOS parallel-plate chambers and a PTW31010 cylindrical chamber were modeled for buildup dose measurement in magnetic fields, using the EGSnrc/cavity code. The irradiation condition was set to a 10 × 10 cm field in a water phantom at a source-to-surface distance (SSD) of 100 cm, using 6-MV photon spectrum.

Dependence of volume dose indices on dose calculation algorithms for VMAT-SBRT plans for peripheral lung tumor.

The purpose of this study was to investigate the dependence of volume dose indices on dose calculation algorithms for volumetric modulated arc therapy (VMAT) for stereotactic body radiotherapy (SBRT) plans to treat peripheral lung tumors by comparing them with those of Monte Carlo (MC) calculations. VMAT-SBRT plans for peripheral lung tumors were created using the Eclipse treatment planning system (TPS) for 24 patients with nonsmall cell lung cancer. VMAT dose distributions for gross tumor volume (GTV), internal target volume (ITV), and planning target volume (PTV) were calculated using the analytical anisotropic algorithm (AAA), the Acuros XB (AXB) algorithm, and a MC algorithm.

Krüppel-like factors 4 and 5 expression and their involvement in differentiation of oral carcinomas.

Proliferation-differentiation balance of epithelial cells is regulated by Krüppel-like factors (KLF) 4 and 5, and the unbalanced expression relates to carcinoma progression. However, little is known about the expression and role in oral carcinomas. This study examined expression of KLF4 and KLF 5 in the carcinomas by immunohistochemistry (n = 67) and the involvement in proliferation and differentiation of carcinoma cells.

Ortho-phthalaldehyde-induced skin mucous membrane damage from inadequate washing.

Because body fluids and blood have a tendency to adhere to transesophageal echo devices, a high level of sterilisation is required when cleaning them. Ortho-phthalaldehyde (OPA) has been widely used in Japan since being approved as a high-level sterilant. The authors report a patient with widespread, severe skin and mucous membrane damage of the lip, tongue, pharynx and oesophagus areas that was attributed to inadequate washing after the sterilisation of a transesophageal echo device with OPA.

Recurrent pancreatitis caused by pancreatobiliary anomalies in children with annular pancreas.

Purpose: Annular pancreas (AP) is usually associated with duodenal obstruction in neonates. Pancreatitis with AP occurs frequently in adults but is rare in children. This article describes pancreatitis in children with AP and pancreatobiliary anomalies and its surgical treatment.

Age-dependent spike localization in various epileptic syndromes.

The electroencephalograms from 276 patients with localization-related epilepsy were analyzed to compare the distribution of spike foci in different age groups. Patients were divided into five groups according to spike location in the frontal, central, temporal, occipital, or multiple cortical regions. The age of peak incidence was earliest in patients with occipital foci, followed by those with central foci and then those with frontal foci.

Hormone-induced granular convoluted tubule-like cells in mouse parotid gland.

Most striated duct (SD) cells in the adult mouse parotid gland (PAG) have a few small secretory granules. These granules, however, are usually too small and sparse to be detected using light microscopy. Our serial studies have suggested that these PAG SD cells belong to a group of hormone-responsive granular duct cells, similar to the granular convoluted tubule (GCT) cells found in the submandibular gland.

Histological analysis of the sublingual gland in rats with streptozotocin-induced diabetes.

This study was designed to examine whether the sublingual gland parenchyma is influenced by the development of insulin-dependent diabetes mellitus. The sublingual glands of rats with streptozotocin-induced diabetes were examined by light and electron microscopy. In order to define the limiting membrane of mucous granules in more detail, samples processed by rapid freezing following by freeze-substitution in addition to chemical fixation were also prepared for electron microscopy.

Hepaticojejunostomy and intrahepatic cystojejunostomy for type IV-A choledochal cyst.

Background: The incidence of choledochal cyst with intrahepatic involvement (Todani's type IV-A cyst) is considerably high. Dilatation of the intrahepatic bile duct is frequently observed around the hepatic hilum, occasionally in the umbilical portion, and rarely in the more upstream intrahepatic bile duct, associated with or without downstream stricture. We recently encountered 2 children with type IV-A cyst associated with upstream intrahepatic ductal dilatation; one with a cystic dilatation of the medial branch arising from the left hepatic duct and another with a cyst of the medial branch arising from the anterior hepatic duct.

Effects of geldanamycin and thalidomide on the Th1/Th2 cytokine balance in mice subjected to operative trauma.

Background: Persistence of postoperative immune dysfunction is a critical problem because it increases the risk of serious infectious complications. The mechanisms of the immune dysfunction that occur initially after non-thermal operative injury remain to be fully elucidated.

Methods: Two mouse models of operative trauma (simple laparotomy to represent minor operative injury and ileocecal resection to represent major operative injury) were used to define the characteristics of initial cytokine synthesis.

[Oriental and European medicine in the local historian Masamichi Teraishi's book].

There was a prevalence of beriberi in the Meiji era. We found articles about Souhaku ASADA, Syouan TOUDA and Jun MATSUMOTO in the Toukayogeidan, written by Masamichi TERAISHI. The book tells about the treatment and its side effects.

[The association between the medical arts of Japan, Korea, and Ming Dynasty China during Toyotomi Hideyoshi's War].

Traditional Korean medicine's pronounced impact on Japan came about as a result of Toyotomi Hideyoshi's war on Korea in the late 16th century. The influences of Korean medicine on Japan were caused by the introduction not only of a large number of medical books printed in the Yi dynasty and the techniques of publication but also those of the people of talent. We researched one doctor who came to Japan during the war of the Bunroku periods.

[The ideographic iteration mark in Senkinho].

In the 7th century, Senkinho was written by Sonshibaku in the Tang dynasty China. This book that was altered in 1066 in the north Sung dynasty China has become known in the world now. However four series of books remained intact, as they were not modified.

Laparoscopic splenopexy for wandering spleen: extraperitoneal pocket splenopexy.

Wandering spleen is a very rare disease. It is a very dangerous condition due to the risk of splenic ischemia from persistent pedicle torsion. Here, we describe a case of wandering spleen diagnosed by ultrasound and computed tomography scans in an 11-year-old boy who suffered from frequent urination and enuresis.

An immunocytochemical study of regeneration of gastric epithelia in rat experimental ulcers.

We experimentally observed the process of regeneration of gastric mucosal cells in ulcers induced by surgical removal of the fundic mucosa of rats. The techniques utilized were immunocytochemistry, laser confocal microscopy, and transmission electron microscopy (TEM). Routine TEM and PAS reaction were used for parietal cells, chief cells, and mucous cells.

Changes in the distribution and fine structure of the intralobular blood vessels of the submandibular gland in the postnatally developing mouse.

Previous studies have shown that the blood vessels supplying the endocrine organs and the mucosa of the intestinal canals change in terms of not only their distribution but also their structure with the development and growth of each organ. We examined changes in the distribution and structure of intralobular blood vessels, including capillaries, throughout the postnatal development of the submandibular gland, an exocrine organ. The mouse submandibular gland from days 0 (birth) to 49 was investigated chronologically and ultrastructurally.

A morphological study of the pacemaker cells of the aganglionic intestine in Hirschsprung's disease utilizing ls/ls model mice.

Hirschsprung's disease is a congenital aganglionic neural disorder of the segmental distal intestine characterized by unsettled pathogenesis. The relationship between Hirschsprung's disease and pacemaker cells (PMC), which almost corresponds to that of the interstitial cells of Cajal (ICC), was morphologically observed at the level of the intermuscular layer corresponding to Auerbach's plexus using ls/ls mice. These mice are an ideal model because of their large intestinal aganglionosis and gene abnormalities, which are similar to the human form of the disease.

Granule types and their morphological changes in terminal cluster and acinar cells in the late pre- and early postnatal rat sublingual gland.

The developmental characteristics of serous cells appearing in the rat sublingual gland from the late prenatal to the early postnatal period were investigated in this study. Particular attention was paid to the morphological changes observed in the secretory granules at the histochemical and ultrastructural level. On prenatal day 18, granules with homogeneous high electron density (Type I granules), and mottled granules (Type II granules) with heterogeneous electron density appeared in the narrow luminar cytoplasm of cells constituting the terminal clusters.

Morphological changes in mouse sublingual gland parenchyma subjected to chorda tympani resection.

Morphological changes in the mouse sublingual gland parenchyma subjected to parasympathetic nerve block were investigated. Mice were subjected to unilateral resection of the chorda tympani, near its point of joining with the lingual nerve. After 1, 2, 3, 5, 10 or 20 weeks, the mice were killed and their sublingual glands were removed and processed for light and electron microscopy.