Publications by authors named "Takanori Ishikawa"
Introduction: Occlusal disharmony induced by deteriorating oral health conditions, such as tooth loss and decreased masticatory muscle due to sarcopenia, is one of the causes of cognitive impairment. Chewing is an essential oral function for maintaining cognitive function not only in the elderly but also in young people. Malocclusion is an occlusal disharmony that commonly occurs in children.
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- The study examined the presence of bucephalid trematodes in golden mussels and freshwater fish from the Tone River system in Japan between 2019 and 2021.
- Researchers collected 1719 mussels and identified a new trematode species, Prosorhynchoides ozakii, affecting mussels and various fish, with infection rates ranging from 0.3% to 100% across multiple sites.
- Genetic analysis of Pr. ozakii indicated that the parasite may have been intentionally introduced multiple times into the river system, as no significant population bottlenecks were observed.
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- The study aimed to assess the stability of miniscrews and analyze the surrounding bone under orthopedic forces using histomorphometric techniques.
- Thirty-two miniscrews were implanted in eight rabbits, with two different groups using auxiliary devices and a control group without, to measure the impact on stability and bone integration over 28 and 56 days.
- Findings showed that miniscrews with auxiliary devices had lower stability values but similar bone-to-implant contact compared to the control group, while the depth of spike implantation increased significantly over time, indicating effective bone formation around the auxiliary devices.
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- A nationwide fish survey in Japan identified metacercariae of the Metagonimus genus using DNA barcoding for molecular species classification.
- The study recognized three cryptic species complexes and proposed four new species based on phylogenetic analysis and morphological characteristics.
- It clarified the taxonomy of Metagonimus species in Japan, revealing a total of 10 species while noting a significant reduction in human cases of metagonimiasis.
Retrotransposons are genetic elements that copy and paste themselves in the host genome through transcription, reverse-transcription, and integration processes. Along with their proliferation in the genome, retrotransposons inevitably modify host genes around the integration sites, and occasionally create novel genes. Even now, a number of retrotransposons are still actively editing our genomes.
View Article and Find Full Text PDFThis study aimed to predict the key genes and pathways that are activated when different types of mechanical loading are applied to osteocytes. mRNA expression datasets (series number of GSE62128 and GSE42874) were obtained from Gene Expression Omnibus database (GEO). High gravity-treated osteocytic MLO-Y4 cell-line samples from GSE62128 (Set1), and fluid flow-treated MLO-Y4 samples from GSE42874 (Set2) were employed.
View Article and Find Full Text PDFA vast number of long-noncoding RNAs (lncRNA) are found expressed in human cells, which RNAs have been developed along with human evolution. However, the physiological functions of these lncRNAs remain mostly unknown. In the present study, we for the first time uncovered the fact that one of such lncRNAs plays a significant role in the differentiation of chondrocytes and, possibly, of osteoblasts differentiated from mesenchymal stem cells, which cells eventually construct the human skeleton.
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