Publications by authors named "Takamichi Kamiyama"
Article Synopsis
- The COVID-19 pandemic has led to significant health impacts, with severe cases often linked to factors like age and underlying health conditions, prompting the exploration of syndecan-1 (SDC-1) as a potential biomarker for predicting outcomes.
- A retrospective study analyzed COVID-19 patients in Fukushima, Japan, measuring SDC-1 levels alongside clinical data to correlate with disease severity and mortality rates.
- Results indicated that higher SDC-1 levels were associated with worse outcomes, suggesting its utility in predicting mortality within 28 days of hospitalization, although further research is necessary to confirm its long-term predictive value.
Article Synopsis
- - The study focused on identifying risk factors for COVID-19 deterioration in unvaccinated individuals under 65 years old during Japan's fifth wave, as many cases occurred in this demographic.
- - Researchers analyzed data from 1,675 patients in Fukushima and created predictive scores to estimate deterioration risk using logistic regression, highlighting significant factors like age, body temperature, oxygen saturation, and comorbidities (diabetes, obesity).
- - The findings indicated that 8.6% of patients experienced deterioration, with predictors including older age, male gender, and various health issues; two risk scores were developed, DOATS and DOAT, to assess patient risk.
Article Synopsis
- A study was conducted to evaluate the efficacy of molnupiravir in hospitalized patients with mild-to-moderate COVID-19 during the Omicron variant surge in Fukushima, Japan, by comparing outcomes between those who used the drug and those who did not.
- After matching molnupiravir users with non-users based on similar characteristics, results showed that the clinical deterioration rate was significantly lower for users (3.90%) compared to non-users (8.40%).
- Multivariate analysis indicated that treatment with molnupiravir independently reduced the risk of deterioration in COVID-19 patients after hospitalization during the Omicron variant phase.
Article Synopsis
- - The study assessed the effectiveness of the monoclonal antibody treatment casirivimab-imdevimab for mild-to-moderate COVID-19 patients during the Delta variant surge in Fukushima, Japan, enrolling 949 patients.
- - Casirivimab-imdevimab users were generally older and had higher rates of health issues like obesity, hypertension, and higher body temperatures compared to non-users.
- - The findings show that receiving casirivimab-imdevimab significantly reduced the risk of clinical deterioration in hospitalized patients, highlighting its potential benefit during COVID-19 hospitalization (odds ratio 0.448).
A previously healthy 6-year-old girl suddenly developed severe abdominal pain and nausea. She was diagnosed with acute gastric volvulus, and a nasogastric tube was inserted to decompress the stomach. The volvulus did not reduce spontaneously; therefore, we performed endoscopic reduction on day 3 and were able to treat her successfully.
View Article and Find Full Text PDFOur purpose was to clarify factors that influence the level of depression of Japanese children with anorectal malformations (ARM). The subjects comprised 66 children with ARM, aged 0-16 years, and their mothers. Patients were divided into three groups (Group 1: aged 0-5 years, Group 2: 6-11 years, and Group 3: 12-16 years).
View Article and Find Full Text PDFObjective: The aim of this study was to investigate the psychological status of Japanese children with congenital anorectal malformation and their mothers to develop appropriate psychiatric interventions.
Method: The subjects comprised 50 children with congenital anorectal malformation aged 0 to 16 years and their mothers. The psychology of children aged 7 to 16 years was investigated by Kovacs' Children's Depression Inventory (CDI).
Excretory dysfunction associated with congenital anal anomalies (a generic term that includes anal atresia and Hirschsprung's disease) is presumed to greatly affect the psychology of the affected children. In this study, we conducted a survey on the psychological status of children with excretory dysfunction, and investigated the relationship between the affected children and their families in addition to their social life. Four children with fecal dysfunction due to a congenital anal anomaly and their mothers were interviewed.
View Article and Find Full Text PDFThis article describes an implantable artificial anal sphincter using shape memory alloys and its in vivo assessment in porcine models. The new design was developed as a low invasive prosthesis with a simple structure to solve the problem of severe fecal incontinence in patients with hypoplastic sphincters or without anal sphincters and especially for ostomates. The artificial anal sphincter consists of two shape memory alloy (SMA) plates as the main functional parts to perform two basic functions when the SMA artificial sphincter is fitted around intestines (i.
View Article and Find Full Text PDFWe report on a girl with biliary atresia (BA) who also suffered with anorectal agenesis without fistula and complicated urogenital malformation. The outcome of patients with these severe anomalies is poor, but she has survived without liver and/or renal transplantation for more than 3 years. A careful treatment plan for each anomaly in addition to prevention of cholangitis and urinary tract infection is indispensable for managing these complicated anomalies.
View Article and Find Full Text PDFBackground/purpose: The authors created a new artificial anal sphincter using a shape memory alloy (AS-SMA) to treat fecal incontinence and evaluated its validity.
Methods: AS-SMA consists of 2 Ti-Ni plates to sandwich the intestine and generates a pressure of 55 mm Hg at its resting position. With the electric power supply, the 2 metals bend to form an almondlike shape making a maximum gap of 33 mm between each other at the temperature of 55 degrees C.
Article Synopsis
- - Surgical treatment for gastroesophageal reflux (GER) in neurologically impaired children is determined by clinical symptoms and various diagnostic tests, while considering the quality of life for both patients and families.
- - Laparoscopic fundoplication is the preferred surgical option for GER, showing effective results in most cases.
- - For patients with severe aspiration issues, a laryngotracheal separation procedure is recommended instead of the standard anti-reflux surgery.
Purpose: The aim of this study was to review 14 patients with congenital esophageal stenosis (CES) from diagnostic and therapeutic points of view.
Methods: From 1976 to 1999, 14 patients with CES were treated at the authors' hospital. In each diagnostic examination, an esophagogram, 24-hour pH monitoring, a manometric study, and an endoscopy were performed.
Tohoku University has developed various artificial organs over the last 30 years. Pneumatic driven ventricular assist devices with a silicone ball valve have been designed by the flow visualization method, and clinical trials have been performed in Tohoku University Hospital. On the basis of these developments, a pneumatic driven total artificial heart has been developed and an animal experimental evaluation was conducted.
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