Early responsiveness to continuous erythropoietin receptor activator predicts renal prognosis and is determined by a novel antioxidative marker in non-dialysis chronic kidney disease: a prospective, observational, single-center study.

Background: Responsiveness to erythropoietin-stimulating agents (ESAs) is important for anemia management in chronic kidney disease (CKD). We assessed the effects of a continuous erythropoietin receptor activator (CERA) on renoprotection beyond anemia management and the correlation between the responsiveness to ESAs and oxidative stress markers in CKD.

Methods: This single-center, prospective, observational study was conducted over 24 months.

Three-dimensional movement analysis of handwriting in subjects with mild hemiparesis.

Objective: To investigate the effects of hemiparesis on handwriting using a 3-dimensional movement analyzer.

Design: Comparative case study.

Setting: Ambulatory care clinic.