Treatment of natto, a fermented soybean preparation, to prevent excessive plasma vitamin K concentrations in patients taking warfarin.

The purpose of this study is to find a method of cooking natto that prevents the appearance of high-plasma vitamin K concentrations after the consumption of natto, so that patients taking warfarin can benefit from eating natto. Five cooking methods were examined to determine which could most effectively decrease the count of the living Bacillus subtilis in natto. Volunteers ate natto or treated natto, and their plasma vitamin K level was measured at 5, 8, 24 and 48 h thereafter.

Lower energy content of human milk than calculated using conversion factors.

Background: Bodyweight gain of formula-fed babies is usually higher than that of breast-fed ones. The energy content of human milk is usually quantified not by direct measurement but by calculation based on The Standard Tables of Food Composition in Japan. For this study, the energy of human milk was quantified in two ways, using a direct measurement and a calculation method.