Publications by authors named "Takahisa Sasho"

Introduction There are several postoperative evaluation methods for anterior cruciate ligament reconstruction (ACLR), and patient-reported outcome measurement (PROM) is one of the most important for evaluating postoperative clinical results. However, conventional PROMs have a high risk of a ceiling effect at one and two years postoperatively and do not accurately reflect functional improvement over time. Therefore, a longitudinal evaluation using PROM with a low risk of ceiling effect is necessary.

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Introduction: The risk of post-traumatic osteoarthritis remains high even after anterior cruciate ligament reconstruction (ACLR). Medial meniscal extrusion (MME) is a valuable clinical sign as an early morphological change. This study aimed to analyze MME before and after ACLR and investigate the factors affecting postoperative MME.

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  • This study focused on the reliability of measuring the dimensions of the anterior talofibular ligament (ATFL) footprint using three-dimensional MRI, which is crucial for effective ankle ligament repair.
  • 20 ankles were analyzed, revealing the sizes of the single-bundle and double-bundle ligament footprints, with specific measurements for both fibular and talar footprints.
  • The results showed excellent reliability in measurements between tests and between different raters, indicating that 3D MRI is a valuable tool for assessing ligament anatomy in vivo.
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  • Hallux valgus (HV), or bunion deformity, is a common condition that affects the forefoot, and early diagnosis is crucial for improving quality of life.
  • A study developed a deep learning model that predicts radiographic measurements of HV using digital foot photographs and evaluates the severity of the deformity.
  • Results showed that the model could effectively estimate important radiographic angles, demonstrating substantial agreement with actual measurements, highlighting its potential for screening HV.
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  • A study evaluated the reliability of measuring lateral ankle ligament attachment locations using 3D magnetic resonance imaging (MRI) in 54 participants with healthy ankles, averaging 43 years old.
  • Measurements were taken for the anterior talofibular ligament and calcaneofibular ligament attachments, revealing high intrarater and interrater reliability.
  • The study concluded that the measurement method provides dependable anatomical data for the lateral ankle ligaments, enhancing understanding of their location in vivo.
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Introduction Restoring knee joint stability and resuming sports activities are important objectives of anterior cruciate ligament (ACL) reconstruction. The maintenance of anterior knee stability after ACL reconstruction is contingent on graft tension. Various devices and techniques have been used to achieve robust tibial graft tendon fixation, and their advantages and disadvantages are established.

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  • - This study focused on treating deep infections in the foot and ankle using a method called continuous local antibiotic perfusion, which involved delivering high doses of gentamicin directly to the infected areas.
  • - Eleven patients underwent surgery and received this treatment from January 2019 to March 2024, with most experiencing successful infection control without needing further operations.
  • - The results showed a mean follow-up period of 40 months, with only two patients developing fungal infections, indicating that local antibiotic perfusion could be an effective option for managing these challenging infections.
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Objective: To assess articular cartilage degeneration in anterior cruciate ligament (ACL) reconstructed knees as detected by MR T1rho and T2 mapping relative to controls and longitudinally at 3 months and 1 year after ACL reconstruction (ACLR).

Design: Twenty-five patients with acute ACL injury were enrolled (13 women and 12 men; mean age 30.8), and 14 healthy controls were selected by sex and age matching.

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Background: Clamping along the transsyndesmotic (TS) axis decreases the risk of malreduction when reducing syndesmotic diastasis. We aimed to measure the difference between the TS axis and the axis determined by the newly proposed fluoroscopic incisura tangent (IT) method. The measurements were compared to those between the TS axis and those based on the center-center (CC) and talar dome lateral (TL) methods.

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Objective: Multilineage differentiating stress-enduring (Muse) cells, a pluripotent stem cell subset of mesenchymal stem cells (MSCs), have shown promise for various tissue repairs due to their stress tolerance and multipotent capabilities. We aimed to investigate the differentiation potential , the dynamics , and the reparative contribution of Muse cells to osteochondral lesions.

Design: Labeled MSCs were cultured and sorted into Muse and non-Muse (MSCs without Muse cells) groups.

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Background: Applying pretension by cyclic knee motion immediately before graft fixation in anterior cruciate ligament (ACL) reconstruction surgery decreases graft elongation during the postoperative course. However, the expected change in graft tension caused by cyclic knee motion remains unclear. We measured graft tension changes caused by cyclic knee motion during double-bundle ACL reconstruction.

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Background/objective: The purpose of this study was to find factors indicating the occurrence of the Segond fracture, a specific type of anterolateral ligament injury.

Methods: From January 2015 to December 2017, we retrospectively reviewed the medical records of patients diagnosed with acute anterior cruciate ligament (ACL) injury who underwent reconstruction within 90 days of injury. Diagnosis of the Segond fracture was determined either by magnetic resonance imaging or plain radiographs.

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  • The study examined whether standardizing ankle stress sonography techniques would reduce measurement variability among different examiners.
  • Fourteen examiners with an average of 8.7 years of ultrasound experience used their preferred methods on three patients, followed by a standardized technique developed in a consensus meeting.
  • Results showed no significant difference in variability or measurement outcomes between the preferred and standardized techniques, indicating that standardization did not effectively reduce variability in ligament length measurements.
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Background: Existing knee related patient reported outcome measurements (PROMs) have overwhelmingly been developed and validated in western chair-based societies, suggesting a potential for a western bias in PROMs evaluation of patients with knee conditions. We, therefore, endeavor to evaluate the responsiveness of the previously developed culturally relevant Japanese version of the knee injury and osteoarthritis outcome score (JKOOS+).

Methods: We enrolled 114 patients scheduled for total knee arthroplasty (TKA) across 8 knee clinics in Japan.

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Background: Placement of clamp forceps along the transsyndesmotic (TS) axis reduces the risk of iatrogenic syndesmotic malreduction during ankle fracture surgery with tibiofibular diastasis. This study aimed to measure the difference between the TS axis and the axis determined by an intraoperative fluoroscopic technique using the center-center (CC) method. We also compared the values obtained when the CC method was performed at different heights from the tibial plafond.

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Objectives: This study aimed to characterize the content of frequently asked questions about the treatment of rheumatoid arthritis (RA) on the internet in Japan and to evaluate the quality of websites related to the questions.

Methods: We searched terms on the treatment of RA on Google and extracted frequently asked questions generated by the Google "people also ask" function. The website that answered each question was also obtained.

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Introduction: We aimed to evaluate the associations of sports participation with self-rated health and depressive symptoms in a nationally representative sample of Japanese adolescents.

Methods: A questionnaire survey was conducted with 1,658 adolescents aged between 12 and 21 years. Sports participation levels were divided into high-frequency, moderate-frequency, low-frequency, and no-participation groups.

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  • Advances in cancer treatment have improved life expectancy, but it is crucial for patients to maintain their daily activities for better quality of life, especially those with motor function issues.
  • A study compared muscle mass between 61 malignant tumor patients and 315 healthy individuals, analyzing factors like body mass index and skeletal muscle mass through bioimpedance analysis.
  • Results showed that while overall skeletal muscle mass index was similar in both groups, female malignant tumor patients had significantly lower trunk muscle mass compared to healthy females, indicating possible motor function impairment despite their maintained performance status.
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Background: This study aimed to quantify the readability and quality of online patient resources on knee osteoarthritis and lumbar spinal stenosis in Japan.

Methods: Three search engines (Google, Yahoo, and Bing) were searched for the terms knee osteoarthritis and lumbar spinal stenosis. The first 30 websites of each search were screened.

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  • Lower limb flexibility (LLF) is important for movement, but assessing it in adolescents is challenging due to physical changes during growth.
  • A five-year study in Japan analyzed 3370 students aged 8-14 by measuring heel-buttock distance, straight leg raising angle, and ankle dorsiflexion to examine the effects of sex and age.
  • Results indicated that girls had better heel-buttock distances but poorer straight leg raising and ankle dorsiflexion than boys, with significant differences in flexibility values based on age and sex, providing reference standards for future assessments.
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We report a 15-year-old female patient who sustained peroneus brevis injury caused by an impingement between the hypertrophied peroneal tubercle and lateral malleolus. The patient had pain for 3 years in the lateral side of her left ankle with unsuccessful conservative treatment. The oblique sagittal images of 3-dimensional magnetic resonance imaging and ultrasonography were useful in depicting the peroneus brevis injury and identifying the location of impingement between the hypertrophied peroneal tubercle and the tip of the lateral malleolus.

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Background: This study aimed to clarify the variability in the measurements of stress sonography of the ankle and determine the effects of examiner experience on the measurements.

Methods: Twenty examiners (10 experienced and 10 beginners) were included in the study. Each examiner performed stress ultrasonography on a patient with a chronic anterior talofibular ligament injury and a patient with an intact ligament using the reverse anterior drawer method.

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Mechanical overload and chemical factors are both related to obesity-induced progression of knee osteoarthritis. The circadian rhythm is related to the development of metabolic syndrome and the progression of osteoarthritis, and the core clock genes nuclear receptor subfamily 1 group D member 1 (NR1D1) and brain and muscle arnt-like protein 1 (BMAL1) are dysregulated in cartilage from patients with osteoarthritis. Here, we focused on NR1D1 and investigated osteoarthritis-related changes and gene expression in a mouse model of diet-induced obesity.

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Background: The coronavirus disease 2019 (COVID-19) pandemic has had a profound impact on children's lifestyles. Some studies have reported psychological changes in children after the pandemic, but information on musculoskeletal problems is scarce. This study aimed to investigate the incidence of knee pain and changes in physical activity after the spread of COVID-19 among elementary and junior high school students in Japan.

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