Publications by authors named "Takahiro Shinki"
We identified the factors associated with home blood pressure (BP) variability in 1933 patients treated with hypertensive drugs (mean age, 67 years; women, 55%). Multivariate regression analysis showed that female gender, advanced age, home BP value, and home heart rate variability were positively associated with home BP variability, whereas home heart rate, body mass index, and duration of antihypertensive treatment were negatively associated with home BP variability. Moreover, not being medicated with amlodipine and being medicated with angiotensin II receptor blockers were associated with increased home systolic BP variability only among patients who were treated for less than 12 months.
View Article and Find Full Text PDFLow-dose (25 mg) or very low-dose (12.5 mg) spironolactone were added among 86 uncontrolled hypertensive patients who were undergoing monotherapy with calcium channel blockers (CCBs), angiotensin-converting enzyme inhibitors (ACEIs), or angiotensin AT1-receptor blockers (ARBs). Morning home systolic/diastolic blood pressure (BP) reduction was similar among the CCB (n = 30, -8.
View Article and Find Full Text PDFThis study compares relationships between each of morning home blood pressure (BP), evening home BP and office BP with electrocardiographic (ECG) abnormalities among treated hypertensive Japanese patients. We defined ECG left ventricular hypertrophy (LVH) as Sokolow-Lyon voltage and/or Cornell voltage duration product. Abnormal T waves and ST segment depression were categorized based on the Minnesota code.
View Article and Find Full Text PDFArticle Synopsis
- A study evaluated over 3,300 hypertensive patients in Japan to compare those with isolated uncontrolled morning hypertension versus those with sustained uncontrolled hypertension, using specific blood pressure cutoff values.
- About 24.6% of patients had isolated uncontrolled morning hypertension, while 42.0% had sustained uncontrolled hypertension, with factors such as alcohol consumption and bathing influencing morning hypertension.
- The findings suggest that classifying morning hypertensive patients based on evening hypertension can help assess overall cardiovascular risk, emphasizing the importance of considering patients' conditions when measuring evening blood pressure.
Objective: The objective of this study was to clarify the factors affecting the morning-evening home systolic blood pressure (BP) difference (home systolic ME dif) in treated hypertensive patients, including evening home BP measuring conditions, based on the data from the Japan Home versus Office BP Measurement Evaluation study.
Methods: The study participants were 3303 essential hypertensive patients (mean age 66.2+/-10.