A New Isocyanosesquiterpene from the Nudibranch Phyllidiella pustulosa.

In the course of our study on the chemical and genetic diversity of the nudibranch Phylidiella pustulosa, we identified a series of isocyanosesquiterpenes. In addition to known sesquiterpenes, we isolated a new molecule 1, the structure of which was elucidated by analyzing NMR and other spectral data. We report the structure and cytotoxicity of compound 1 herein.

[Utility of the number of steps walked daily as a health promotion parameter in community-dwelling elderly persons].

Aim: To clarify the usefulness of the number of steps walked daily as a health promotion parameter in the elderly.

Methods: The study was performed at five welfare centers for the elderly in the suburban area of Takatsuki-city, Japan. Subjects comprised 339 community-dwelling persons (96 men and 243 women) aged 60-89 years.

Factors associated with good self-rated health of non-disabled elderly living alone in Japan: a cross-sectional study.

Background: Self-rated health (SRH) is reported as a reliable predictor of disability and mortality in the aged population and has been studied worldwide to enhance the quality of life of the elderly. Nowadays, the elderly living alone, a particular population at great risk of suffering physical and mental health problems, is increasing rapidly in Japan and could potentially make up the majority of the aged population. However, few data are available pertaining to SRH of this population.

[Predictors of houseboundedness among elderly persons living autonomously in a rural community].

Aim: The housebound state is a risk factor for disability. This prospective study aimed to determine factors predictive of houseboundedness in the elderly, with an ultimate goal of preventing this condition.

Methods: A self-report questionnaire pertaining to mental, physical and social status was administered to 732 community-dwelling elderly persons (313 men, 419 women; age range, 65-85 years) in October 2000.

Urinary yttrium excretion and effects of yttrium chloride on renal function in rats.

Evaluation of yttrium exposure in biological samples has not been fully examined. To evaluate yttrium nephrotoxicity, yttrium chloride was orally administered to male Wistar rats and the urine volume (UV) and N-acetyl-beta-D-glucosaminidase (NAG) and creatinine excretion (Crt) were measured in 24-h urine samples. The urinary yttrium concentration and excretion rate were determined by inductively coupled plasma-argon emission spectrometry (ICP-AES).

Determination of reference concentrations of strontium in urine by inductively coupled plasma atomic emission spectrometry.

Objective: The aim of this study was to establish reference concentrations of urinary strontium by inductively coupled plasma atomic emission spectrometry (ICP-AES).

Methods: For the determination of strontium, urine samples were collected from healthy Japanese (n=146; 115 males, 31 females; mean age, 33±9 years; age range, 18 to 58 years). The urine samples stored at or below -20°C were thawed with incubation at 40°C for 30 min and sediments were dissolved by vigorous shakings.

Measles encephalitis in early pregnancy and after delivery.

We present two cases of measles encephalitis, one in early pregnancy and one after delivery. In case 1, the patient became unconscious 6 days after the appearance of a rash and was treated with glycerol and immunoglobulin. In case 2, the patient became unconscious 6 days after the appearance of a rash and was also treated with glycerol and immunoglobulin.