Diagnostic utility of a homeobox transcription factor, engrailed homeobox 1 (En1) in the histopathology of salivary gland neoplasms was studied. The expression of En1 was immunohistochemically examined in 51 cases of adenoid cystic carcinoma (AdCC) and 143 cases of other salivary gland neoplasms. In all 51 AdCCs, En1 was expressed in 30-100% of tumor cells.
View Article and Find Full Text PDFObjectives: The diagnostic utility of En1 in the histopathologic differentiation of eccrine porocarcinoma (EPC) from invasive squamous cell carcinoma (SCC) was investigated.
Methods: Expression of En1 and CK19 in 16 cases of EPC was immunohistochemically examined and compared with that in 32 cases of SCC.
Results: In all 16 EPCs, En1 was expressed in 3% to 100% of tumor cells.
Previous studies have shown that reappraisal (changing the way that one thinks about emotional events) is an effective strategy for regulating emotion, compared with suppression (reducing emotion-expressive behavior). In the present study, we investigated relative left frontal activity when participants were instructed to use reappraisal and suppression of negative emotion, by measuring frontal alpha asymmetry (FAA). Two electroencephalography (EEG) experiments were conducted; FAA was analyzed while 102 healthy participants (59 men, 43 women) watched negative images after being instructed to perform reappraisal (Experiment 1) and suppression (Experiment 2).
View Article and Find Full Text PDFThe immunological mechanism of Helicobacter pylori-induced chronic gastritis is still unknown. In our previous study using a novel anti-H. pylori monoclonal antibody and surgically resected stomachs from gastric cancer patients, we succeeded to detect H.
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