Publications by authors named "Takahiro Hakozaki"

Background: Sleep deprivation is frequently observed among critically ill patients, and sleep aids still lack robust evidence of efficacy. Thus, the present randomised controlled study aimed to investigate the effectiveness of weighted blankets as non-pharmacological sleep aids for patients in the intensive care unit.

Methods: Patients scheduled to be admitted to the intensive care unit after elective hepatobiliary-pancreatic surgery were randomly assigned to one of two groups: a weighted blanket group or a normal blanket group.

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  • - The study investigated the relationship between the high frequency variability index (HFVI)/analgesia nociception index (ANI) and postoperative pain in patients undergoing video/robotic-assisted thoracoscopic surgery with nerve blocks under general anesthesia.
  • - Researchers looked at various measurements of HFVI/ANI and whether they could predict maximum postoperative pain levels and morphine usage, analyzing data from 48 patients.
  • - The findings indicated no significant correlation between HFVI/ANI and postoperative pain ratings or morphine consumption, suggesting that predicting postoperative pain in these cases using HFVI/ANI is challenging.
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Background: Advancing a tracheal tube over a tracheal tube exchanger into the trachea frequently causes difficulties because of the tube impingement on laryngeal structures. In the present study, we measured the resistance of tube advancement both objectively and subjectively with a variety of combinations of tube exchanger sizes and tracheal tubes using a manikin simulator.

Methods: Lubricated 7.

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In communicating aortic dissection, if only the entry or reentry is closed, residual blood flow may cause enlargement of the false lumen. In this case, surgeons were unable to occlude the entry with a stent graft due to the strong flexion of the bilateral common iliac arteries, so they closed only the reentry in the hope that blood flow from the reentry would be high. Unfortunately, due to the high blood flow from the entry, the false lumen was enlarged.

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  • Post-intensive care syndrome (PICS) is a growing concern for critically ill COVID-19 patients, but its prevalence and risk factors are not well understood.
  • A multicenter study surveyed ventilated COVID-19 patients about their cognitive and emotional health, finding that around 60% experienced PICS months after leaving the ICU.
  • Key risk factors identified included the presence of delirium and the length of time on mechanical ventilation, highlighting the need for further support for these patients post-ICU.
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Background: The use of pressure-controlled ventilation (PCV) for anesthesia management is becoming more commonly used. Chest drainage is commonly performed after thoracic surgery, and the negative pressure it generates might affect the transpulmonary pressure (TPP). In the present study, we investigated how chest drainage could affect ventilating conditions during PCV.

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  • The case presented involves a 70-year-old man undergoing lower lobectomy with pressure-controlled ventilation (PCV) during one lung ventilation (OLV) to avoid high airway pressure.
  • After placing a chest drainage tube, there was a dramatic drop in tidal volume (TV) from 450 ml to 250 ml, prompting a switch to volume-controlled ventilation to maintain the target TV.
  • The subsequent re-thoracotomy revealed no significant issues, suggesting that the decrease in TV could be attributed to increased negative pressure in the chest cavity affecting lung volume post-surgery.
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The Sanuki airway is a single-use intubation oral airway designed for fiberoptic bronchoscope intubation. Sanuki airway has a bite block function and a wide lumen for the tracheal tube to pass through. Here, three cases are reported in which Sanuki airway was used for oral fiberoptic bronchoscope intubation.

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Inadvertently, the reference [8] was published incorrectly in the original publication of the article. The correct reference [8] is provided below.

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Purpose: Little information is available on the predictive ability of previously published pharmacokinetic models of dexmedetomidine in patients under spinal anesthesia. We evaluated nine published pharmacokinetic models that were constructed in different study settings.

Methods: Sixteen patients received dexmedetomidine infusions after spinal anesthesia according to the manufacturer's recommended regimen (6 µg/kg/h over 10 min followed by 0.

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  • A study evaluated how intravenous indigo carmine affects noninvasive and continuous total hemoglobin (SpHb) measurement in 18 patients undergoing gynecologic surgery.
  • Patients received a 5 mL injection of 0.4% indigo carmine during surgery, and their SpHb levels were measured before and after the injection.
  • The results showed no significant change in SpHb concentrations after the injection, indicating that the Revision L sensor effectively measured hemoglobin levels without interference from indigo carmine.
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  • The study examined how an intravenous injection of indigo carmine affects noninvasive total hemoglobin (SpHb) measurements in 21 patients undergoing gynecologic surgery.
  • Results showed a decrease in SpHb from 10 g/dL to a minimum of 8.3 g/dL, with the lowest level reached 4 minutes after the injection, and recovery to normal levels took about 15 minutes.
  • The decrease was more pronounced in patients with a perfusion index (PI) lower than 1.4, highlighting the need for caution when assessing SpHb following indigo carmine administration.
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We carried out a retrospective investigation on the effect of obesity on dexmedetomidine (DEX) requirements when administered with fentanyl (FEN) during mechanical ventilation after major surgeries. After Institutional Review Board approval, 14 obese patients with a body mass index (BMI) ≥ 30 kg/m(2) and the same number of non-obese patients with similar backgrounds to the obese patients were selected from medical records. Doses of DEX in the first 48 h or until the end of sedation or extubation were calculated for comparison.

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Ultrasound-guided subcostal transversus abdominis plane block (TAPB) is widely used for abdominal surgery; however, arterial plasma concentration of the anesthetic ropivacaine after the blockade is still unclear. We evaluated ropivacaine concentration after subcostal TAPB in adult patients undergoing upper abdominal surgery. Twelve patients with American Society of Anesthesiologists physical status 1-2 were enrolled.

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  • * Using microdialysis, researchers found that midazolam significantly decreased acetylcholine levels and kept them lower even after stopping, while propofol also lowered levels but they rebounded quickly after its infusion stopped.
  • * Dexmedetomidine reduced acetylcholine release, but this effect wasn't significant; overall, midazolam has a longer-lasting impact on acetylcholine levels compared to propofol, despite both causing sedation.
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We report the use of ultrasound-guided bilateral brachial plexus block in a patient with bilateral radius fractures. An axillary block was performed on the patient's right and a supraclavicular block on her left using an in-plane (long-axis) needle insertion technique. Into each side was injected 20 ml 0.

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Because the liver is one of the most important vital organs, liver dysfunction/failure gives great influence on the operative prognosis. Therefore, it is necessary to evaluate the liver function preoperatively. There are many laboratory tests to evaluate hepatobiliary status, including broad categories of hepatobiliary pathology: hepatitis, hepatobiliary dysfunction, or insufficient protein synthesis.

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Background: To evaluate the performance of the Airway Scope, we studied the time to complete endotracheal intubation performed by senior residents in anesthesiology.

Methods: The trachea of the patient was intubated using the Airway Scope (n = 90) or the Macintosh laryngoscope (n = 81).

Results: The time to complete endotracheal intubation was 42 +/- 23 sec with the Airway Scope and 41 +/- 20 sec with the Macintosh laryngoscope.

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