Publications by authors named "Takafumi Iguchi"

Article Synopsis
  • Predicting postoperative recurrence in non-small cell lung cancer (NSCLC) is crucial for improving treatment strategies, and previous research has linked PD-L1 expression to recurrence risks.
  • This study utilized machine learning on clinical data from 647 NSCLC patients to evaluate how well PD-L1 expression predicts recurrence after surgery, using various analytical methods.
  • The results showed that the random forest model was the most effective in prediction, confirming that higher levels of PD-L1 expression are associated with increased risk of recurrence, which could enhance clinical decision-making for NSCLC treatment.
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Subpleural peripheral lung regions are mainly nourished by pulmonary arteries. Herein, we report a case in which pleural infection after pulmonary embolism caused circulation failure in the subpleural lung parenchyma (SLP) and massive desquamation of the SLP.

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Thoracic SMARCA4-deficient undifferentiated tumours are ordinarily found as a huge mass with systemic metastasis, and the prognosis is poor. The potential of immunotherapy for these unresectable tumours has been reported. An asymptomatic 68-year-old man with a smoking history had a left lung mass without distant metastasis and underwent complete resection.

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The present study investigated the effects of the dietary addition of the protease preparations derived from on the colonic luminal environment. Rats were fed a 30% beef tallow diet with or without the protease preparations, including Amano protease (protease A 'Amano SD', neutral proteases from spp.) or orientase (orientase AY, acid proteases from ) at the dose of 0.

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This study investigated the effects of dietary supplementation with burdock powder and Aspergillus awamori-fermented burdock powder at 5% on the intestinal luminal environment and body fat in rats fed a high-fat (HF) diet. Food intake and growth were unaffected by dietary manipulation. Consumption of the burdock and fermented burdock diets significantly elevated fecal IgA and mucins (indices of intestinal immune and barrier functions) and reduced fecal lithocholic acid (a risk factor for colon cancer) (p<0.

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We have found that fermented barley extract (FBE), prepared from barley shochu residue, alleviates allergic rhinitis in OVA-sensitized mice. In this study, we examined to determine whether FBE suppresses the development of atopic dermatitis (AD)-like skin lesions in NC/Nga mice. The development of AD-like skin lesions in a 5% FBE containing diet group was significantly inhibited, and scratching behavior, one of aggravating factors, was also suppressed.

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