Interfacial modification of NaCoO positive electrodes with inorganic oxides by simple mixing and the effects on all-solid-state Na batteries.

All-solid-state Na polymer batteries are desired as the next generation of high-capacity batteries owing to their high safety and abundant resources. However, the degradation of the positive electrode/electrolyte interface with cycling leads to a decrease in capacity and a significant increase in interfacial resistance. In this study, to suppress the interfacial degradation, we prepared positive electrode sheets through a combination of simple mixing and pasting with the addition of binders and conductive additives, using NaCoO coated with two types of inorganic oxides as the active material.

A prospective compound screening contest identified broader inhibitors for Sirtuin 1.

Potential inhibitors of a target biomolecule, NAD-dependent deacetylase Sirtuin 1, were identified by a contest-based approach, in which participants were asked to propose a prioritized list of 400 compounds from a designated compound library containing 2.5 million compounds using in silico methods and scoring. Our aim was to identify target enzyme inhibitors and to benchmark computer-aided drug discovery methods under the same experimental conditions.