Publications by authors named "Tak Pan Ng"
Article Synopsis
- Transarterial chemoembolization is a common treatment for intermediate-stage hepatocellular carcinoma (HCC), and this study explored using a new hydrogel material for better outcomes.
- In a mouse model, the hydrogel, especially when loaded with cisplatin, significantly reduced tumor growth and improved indicators of tumor cell death compared to other treatments.
- The hydrogel not only blocked blood flow to the tumor but also integrated into tumor vessels over time, leading to less tumor proliferation and angiogenesis, making it a promising agent for future HCC treatments.
Endocytosis is the process by which substrates enter a cell without passing through the plasma membrane but rather invaginate the cell membrane and form intracellular vesicles. Rab7 regulates endocytic trafficking between early and late endosomes and between late endosomes and lysosomes. LeRab7 in Lentinula edodes is strongly homologous to Rab7 in Homo sapiens.
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