Regional Nerve Blocks Improve Pain and Functional Outcomes in Hip Fracture: A Randomized Controlled Trial.

Objectives: To compared outcomes of regional nerve blocks with those of standard analgesics after hip fracture.

Design: Multisite randomized controlled trial from April 2009 to March 2013.

Setting: Three New York hospitals.

Carraguard Vaginal Gel Safety in HIV-Positive Women and Men in South Africa.

Objective: To assess the safety of the candidate microbicide Carraguard gel in HIV-positive women and men.

Design: A randomized, placebo-controlled, triple-blinded clinical trial of Carraguard gel when applied vaginally once per day for 14 intermenstrual days by sexually abstinent and sexually active HIV-positive women; and when applied directly to the penis once per day for 7 days by sexually abstinent HIV-positive men.

Methods: In each cohort (n = 20 per cohort), participants were randomized to Carraguard, methylcellulose placebo, or no product (1:1:1).