Publications by authors named "Taiwo Gbemisola Bello"
Article Synopsis
- Hypertension is a common issue for people with diabetes, and this study examines how composite biscuits made from acha and sandpaper leaf flours affect blood pressure and certain enzyme activities in hypertensive/diabetic rats.
- The research involved seven groups of experimental rats, with three groups on a standard diet and four groups fed the composite biscuits for 14 days, leading to measurements of their mean arterial blood pressure and various biochemical markers.
- Results showed that rats on the composite biscuit diet had lower mean arterial blood pressure and improved enzyme activities and nitric oxide levels compared to untreated rats, suggesting these biscuits can potentially help manage hypertension and diabetes.
Acha grains and sandpaper leaf are commonly used by locals for diabetes and hypertension management, respectively. However, this study sought to produce biscuits from acha-sandpaper leaf composite flour and evaluate their ameliorative potentials in streptozotocin (STZ)/Nω-nitro-l-arginine methylester hydrochloride (l-NAME)-induced hypertensive-diabetic rats. Group I (non-diabetic/normotensive), group II (negative control), group III (positive control) rats were placed on standard drugs, and groups IV-VII rats were placed on formulated biscuits supplemented with 0%, 1.
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