Health-related Quality of Life in Acromegaly Patients: Results from Generic and Disease-specific Questionnaires.

Introduction: Acromegaly is associated with high morbidity, but still controversial impact on the overall quality of life (QoL).

Material And Methods: We evaluated QoL using a generic (SF-36) and a disease-specific questionnaire (AcroQoL) in an acromegalic cohort.

Results: Sixty-nine patients answered the questionnaires and had their records reviewed.

The acromegalic spine: fractures, deformities and spinopelvic balance.

Introduction: Axial skeleton arthropathy and osteoporotic vertebral fractures are common findings in acromegalic patients and can result in severe spinal deformity.

Objective: To investigate the presence of spinal fractures and deformities, sagittal imbalances, and spinopelvic compensatory mechanisms in acromegalics.

Patients And Methods: 58 patients with acromegaly from a referral neuroendocrinology center were prospectively evaluated by panoramic spine radiographs to detect the presence of fractures and scoliosis, to measure thoracic kyphosis, lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT) and sagittal vertical axis (SVA).