Prolonged survival with mitral valve plasty for acute mitral regurgitation due to mitral valve dysplasia and chordal rupture in a young small dog: A case report.

Unlabelled: : We aimed to report the second case of mitral valve plasty (MVP) for acute mitral regurgitation (MR) due to mitral valve dysplasia in a young small dog.

Case Description: A 5-month-old female Jack Russell, weighing 3.5 kg, presented with dyspnea and collapse upon excitation.

Simultaneous Measurement of Amino Acid Enantiomers in Aged Mouse Brain Samples by LC/MS/MS Combined with Derivatization Using -(5-Fluoro-2,4-dinitrophenyl)-l-leucinamide (l-FDLA).

D-amino acids have distinct roles from their l-enantiomer. In particular, some D-amino acids function as agonists or antagonists of neuronal receptors and are involved in higher brain functions. Thus, it is important to precisely measure the levels of these amino acid enantiomers in cells and tissues.

Disilaruthena- and Ferracyclic Complexes Containing Isocyanide Ligands as Effective Catalysts for Hydrogenation of Unfunctionalized Sterically Hindered Alkenes.

Disilaferra- and disilaruthenacyclic complexes containing mesityl isocyanide as a ligand, 3' and 4', were synthesized and characterized by spectroscopy and crystallography. Both 3' and 4' showed excellent catalytic activity for the hydrogenation of alkenes. Compared with iron and ruthenium carbonyl analogues, 1' and 2', the isocyanide complexes 3' and 4' were more robust under the hydrogenation conditions, and were still active even at higher temperatures (∼80 °C) under high hydrogen pressure (∼20 atm).

Cardiovascular and renal effects of carvedilol in dogs with heart failure.

To determine the acute effects of carvedilol (beta-blocker) on cardiovascular and renal function and its pharmacokinetics in dogs. Fifteen mature mongrel dogs (7-15 kg) of both sexes were used in these experiments. Eight dogs served as controls, and seven dogs served as iatrogenic mitral regurgitation (MR) experimental animals.