[Apelin-13 promotes mitochondrial autophagy and improves rat myocardial ischemia-reperfusion injury by blocking PINK1/parkin signaling pathway].

Objective To investigate the effect of adipocytokine Apelin-13 (AP13) on mitochondrial autophagy in myocardial ischemia reperfusion injury (MIRI) and its mechanism. Methods MIRI model was established by ligating the coronary artery branches of rats. The rats are divided into sham group, AP13-treated sham group, MIRI group and AP13-treated MIRI group.