Publications by authors named "Tai-Qing Lu"
[Expression and functions of long non-coding RNA actin filament-associated protein 1-antisense RNA1 in oral squamous cell carcinoma].
Hua Xi Kou Qiang Yi Xue Za Zhi
December 2019
Article Synopsis
- The study investigates the long non-coding RNA AFAP1-AS1 and its role in oral squamous cell carcinoma (OSCC), revealing higher expression levels in cancerous tissues compared to normal cells, indicating its potential as a biomarker.
- A correlation was found between high levels of AFAP1-AS1 and poor clinical outcomes, including lower survival rates and advanced disease characteristics like differentiation and lymphatic metastasis.
- Experimental silencing of AFAP1-AS1 led to reduced cell proliferation, invasion, and migration in OSCC cell lines, suggesting that targeting this lncRNA could be a promising therapeutic strategy for improving patient outcomes.
[Study of psychological distress and quality of life in patients with oral cancer].
Shanghai Kou Qiang Yi Xue
October 2018
Article Synopsis
- The study investigates how various factors, including age and treatment history, impact the quality of life and psychological distress in oral cancer patients.
- Out of 250 surveyed patients, a significant portion experienced high levels of distress, particularly those who were younger or had undergone more extensive surgeries like jaw resection.
- The findings suggest that emotional and physical well-being in these patients is closely linked, with negative correlations between psychological distress and quality-of-life metrics like pain and anxiety.