Publications by authors named "Tai-Hang Wang"
Background: The NOD-, LRR- and pyrin domain‑containing 3 (NLRP3) inflammasome is a critical component of the innate immune system. It has been known to play an important role in the carcinogenesis and prognosis of breast cancer patients. While the clinical evidence of the relationship between NLRP3 inflammasome activation and long-term survival is still limited, the possible roles of parenchymal or immune-stromal cells of breast cancer tissues in contributing to such carcinogenesis and progression still need to be clarified.
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- Postoperative delirium (POD) is a frequent issue in older patients, marked by sudden problems with attention and awareness, and this study examines the effects of remimazolam tosylate compared to propofol on POD rates after surgery.
- The research is a randomized controlled trial involving 636 elderly individuals undergoing major non-cardiac surgery, assessing POD occurrence within five days following anesthesia with either drug.
- The study has ethical approval, aims to collect informed consent, and plans to disclose its findings through scientific conferences and peer-reviewed journals.
Objective: To explore the role and mechanism of the Kelch sample related protein-1-nuclear factor erythroid-2 related factor 2/antioxidant response element (Keap1-Nrf2/ARE) signaling pathway in protection of dexmedetomidine (DEX) preconditioning against myocardial ischemia/reperfusion injury (MIRI).
Methods: A total of 70 male SD rats were randomly divided into seven equal groups (n=10): blank control (S group), ischemia/reperfusion injury (C group), DEX preconditioning (DEX group), tertiary butylhydroquinone (tBHQ) control (tBHQ group), combined tBHQ and DEX preconditioning (tBHQ+DEX group), all-trans retinoic acid (ATRA) control (ATRA group), and combined ATRA and DEX preconditioning (ATRA+DEX group). Serum creatine kinase-MB (CK-MB) and cardiac troponin I (cTnI) concentrations were measured by ELISA kits, and the infarct size (IS) was assessed by Evan's blue and 2,3,5-triphenyltetrazolium chloride (TTC) staining.
Plant survival in the terrestrial ecosystem is influenced by both beneficial and harmful microbes. spp. are a group of filamentous fungi that promote plant growth and resistance to harmful microbes.
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