Synergistic effects of NiPtCo/TiWO hybrid electrocatalysts for accelerating formic acid electro-oxidation performance.

We herein report the fabrication strategy of a robust catalyst for the formic acid electro-oxidation reaction (FAOR) combining the advantages of a TiO-related support and the synergistic effects of NiPtCo alloy. With the predominant dehydrogenation pathway, the NiPtCo/TiWO catalyst shows remarkable FAOR mass activity and specific activity of 0.45 A mg and 1.

Factors associated with transition to a nursing home in older adults living in naturally occurring retirement communities.

Background: Naturally occurring retirement communities (NORCs) are geographic areas (generally high-rise buildings or neighborhoods) that have a high concentration of individuals 65 years and older. Supportive service programs in NORCs can address resident needs and delay nursing home (NH) admission but understanding what factors are associated with NORC residents requiring NH admission is needed to tailor such programs. Our aim was to examine individual- and neighborhood-level factors associated with NH wait-list status in NORC residents in Ontario.

Using Blood Wisely: lessons learnt in establishing a national implementation programme to reduce inappropriate red blood cell transfusion.

Background: Up to 50% of blood is transfused inappropriately despite best evidence. In 2020, Choosing Wisely Canada launched a major national programme, 'Using Blood Wisely', the aim was to engage hospitals to audit their red blood cell transfusion use against national benchmarks and participate in a programme to decrease inappropriate use.

Study Design: Using Blood Wisely is a quality improvement programme including national benchmarks, an audit tool, recommended evidence-based effective interventions and a designation to reward success.

Lattice Strain and Composition Effects on the Methanol Oxidation Performance of Platinum-Ruthenium-Nickel Ternary Nanocatalysts.

Ternary Pt-based structures are a positive progress in addressing the disadvantages of monometallic and bimetallic Pt-based alloys for the electrochemical oxidation process of simple alcohols, which is a vital half-reaction in fuel cell technologies. We herein report a facile NaBH-assisted ethylene glycol reduction process for fabricating a series of nanosized PtRuNi ternary alloys to explore the relationship between physicochemical properties and electrocatalytic behaviors for the acidic methanol oxidation reaction (MOR). Owing to a balance between lattice strain and synergistic effects, the PtRuNi/C electrocatalyst shows the highest MOR efficiency with the mass activity/specific activity of 844.

Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss.

There are currently no surgical procedures that effectively address the treatment of volumetric muscle loss (VML) injuries that has motivated the development of implantable scaffolding. In this study, the effectiveness of an allogenic scaffold fabricated using fibers built from the extracellular matrix (ECM) collected from muscle fibroblast cells during growth in culture was explored using a hindlimb VML injury (tibialis anterior muscle) in a rat model. Recovery outcomes (8 weeks) were explored in comparison with unrepaired controls as well previously examined allogenic scaffolds prepared from decellularized skeletal muscle (DSM) tissue ( = 9/sample group).

Integrating Low Pt-Based Ternary NiRuPt Nanoalloy on Hybrid TiO-Based Oxide-Carbon Composite for Enhanced Ethanol Oxidation.

Ternary NiRuPt nanoscale alloy on hybrid TiIrO-C composite is herein reported to overcome the high cost and tenuous catalytic efficiency of anode catalysts in direct ethanol fuel cells. The small-size NiRuPt alloy is anchored on the TiIrO-C surface via a NaBH-ethylene glycol-assisted coreduction route. Benefiting from advantages of favorable structure and synergistic effects of compounds, the NiRuPt/TiIrO-C catalyst exhibits high electrocatalytic performance for the ethanol electro-oxidation reaction (EOR) with mass activity of 720.

Transcriptome profiling of a synergistic volumetric muscle loss repair strategy.

Volumetric muscle loss overwhelms skeletal muscle's ordinarily capable regenerative machinery, resulting in severe functional deficits that have defied clinical repair strategies. In this manuscript we pair the early in vivo functional response induced by differing volumetric muscle loss tissue engineering repair strategies that are broadly representative of those explored by the field (scaffold alone, cells alone, or scaffold + cells) to the transcriptomic response induced by each intervention. We demonstrate that an implant strategy comprising allogeneic decellularized skeletal muscle scaffolds seeded with autologous minced muscle cellular paste (scaffold + cells) mediates a pattern of increased expression for several genes known to play roles in axon guidance and peripheral neuroregeneration, as well as several other key genes related to inflammation, phagocytosis, and extracellular matrix regulation.

Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury.

This study was designed to test the hypothesis that in addition to repairing the architectural and cellular cues via regenerative medicine, the delivery of immune cues (immunotherapy) may be needed to enhance regeneration following volumetric muscle loss (VML) injury. We identified IL-10 signaling as a promising immunotherapeutic target. To explore the impact of targeting IL-10 signaling, tibialis anterior (TA) VML injuries were created and then treated in rats using autologous minced muscle (MM).

Mixed-oxide-containing composite-supported MoPt with ultralow Pt content for accelerating hydrogen evolution performance.

The hybridization of MoPt with ultralow Pt content (2.81 wt%) on a rutile TiIrO-C composite (MoPt/TiIrO-C) is fabricated by a self-growth-assisted reduction route, serving as an efficient catalyst for the hydrogen evolution reaction (HER). Due to unique structural features, the MoPt/TiIrO-C catalyst requires an extremely low overpotential of 21.

A method to detect influencers in social networks based on the combination of amplification factors and content creation.

A social network is one of the efficient tools for information propagation. The content is the bridge between the product and its customers. Evaluating the user's content creation is a valuable feature to improve information spreading on the social network.

One-pot production of a sea urchin-like alloy electrocatalyst for the oxygen electro-reduction reaction.

Designing a cost-effective catalyst with high performance towards the oxygen electro-oxidation reaction (ORR) is of great interest for the development of green energy storage and conversion technologies. We report herein a facile self-assembly strategy in a mild reducing environment to realize an urchin-like NiPt bimetallic alloy with the domination of the (111) facets as an efficient ORR electrocatalyst. In the rotating-disk electrode test, the as-obtained NiPt nanourchins (NUCs)/C catalyst demonstrates an increase in both onset potential (0.

Implementation, spread and impact of the Patient Oriented Discharge Summary (PODS) across Ontario hospitals: a mixed methods evaluation.

Background: Traditional discharge processes lack a patient-centred focus. This project studied the implementation and effectiveness of an individualized discharge tool across Ontario hospitals. The Patient Oriented Discharge Summary (PODS) is an individualized discharge tool with guidelines that was co-designed with patients and families to enable a patient-centred process.

In vivo testing of an injectable matrix gel for the treatment of shoulder cuff muscle fatty degeneration.

Introduction: Extracellular matrix (ECM) gels have shown efficacy for the treatment of damaged tissues, most notably cardiac muscle. We hypothesized that the ECM gel prepared from skeletal muscle could be used as a treatment strategy for fatty shoulder cuff muscle degeneration.

Methods: We conducted experiments to (1) evaluate host biocompatibility to ECM gel injection using a rat model and (2) examine the effect of ECM gel injection on muscle recovery after delayed repair of a released supraspinatus (SSP) tendon using a rabbit model.

Wire-like Pt on mesoporous TiWO Nanomaterial with Compelling Electro-Activity for Effective Alcohol Electro-Oxidation.

Finding out robust active and sustainable catalyst towards alcohol electro-oxidation reaction is major challenges for large-scale commercialization of direct alcohol fuel cells. Herein, a robust Pt nanowires (NWs)/TiWO electrocatalyst, as the coherency of using non-carbon catalyst support and controlling the morphology and structure of the Pt nanocatalyst, was fabricated via an effortless chemical reduction reaction approach at room temperature without using surfactant/stabilizers or template to assemble an anodic electrocatalyst towards methanol electro-oxidation reaction (MOR) and ethanol electro-oxidation reaction (EOR). These observational results demonstrated that the Pt NWs/TiWO electrocatalyst is an intriguing anodic electrocatalyst, which can alter the state-of-the-art Pt NPs/C catalyst.

High Conductivity and Surface Area of Mesoporous TiWO₂ Materials as Promising Catalyst Support for Pt in Proton-Exchange Membrane Fuel Cells.

In this work, mesoporous TiWO₂ materials with high conductivity and surface area as promising catalyst support for Pt in Proton-Exchange Membrane Fuel Cells (PEMFCs) were synthesized via a single-step solvothermal process at low-temperature without using any surfactants or stabilizers. The characterizations of material are measured via XRD, TEM, SEM-EDS, and BET as well as electronic conductivity measurement. As a result, TiWO₂ formed a homogenous solid solution with mesoporous anatase-TiO₂ structure and uniformly spherical nanoparticles morphology of about ~10 nm diameter, together with a high electrical conductivity of 0.

Advanced TiWO₂ Nanoparticles Prepared via Solvothermal Process Using Titanium Tetrachloride and Tungsten Hexachloride as Precursors.

The degradation of Pt-based catalysts is considered as the main barrier to the commercialization of fuel cells. M-doped TiO2 (M is a transition metal) has been investigated to improve the stability of electrocatalysts. Recently, W-doped TiO2 materials have been found as a good catalyst support for the photocatalyst applications but their application in Proton-exchange membrane fuel cell application has rarely been reported.

One-Step Hydrothermal Synthesis of a New Nanostructure TiIr₃O₂ for Enhanced Electrical Conductivity: The Effect of pH on the Formation of Nanostructure.

Non-carbon materials are considered as the promising candidates for carbon-based catalyst support to increase the durability of proton exchange membrane fuel cells (PEMFCs). Due to the high stability and good electrical conductivity of TiO2, M-doped TiO2 (M is transition metals: Mo, Ru, V, W) is an emerging candidate for Pt nanoparticles support on the cathode side of PEMFCs. In this research, the synthesis mechanism of Ti0.

Impact of patient-centered discharge tools: A systematic review.

Background: Patient-centered discharge tools provide an opportunity to engage patients, enhance patient understanding, and improve capacity for self-care and postdischarge outcomes.

Purpose: To review studies that engaged patients in the design or delivery of discharge instruction tools and that tested their effect among hospitalized patients.

Data Sources: We conducted a search of 12 databases and journals from January 1994 through May 2014, and references of retrieved studies.

Implementing Patient-Oriented Discharge Summaries (PODS): A Multisite Pilot Across Early Adopter Hospitals.

Communication gaps when patients transition from hospital to either home or community can be problematic. Partnership between Toronto Central Local Health Integration Network (TC LHIN) and OpenLab addressed this through the Patient-Oriented Discharge Summaries (PODS) project. From January through March 2015, eight hospital departments across Toronto came together to implement the PODS, a tool previously developed through a co-design process involving patients, caregivers and providers.

Co-creating patient-oriented discharge instructions with patients, caregivers, and healthcare providers.

For hospitalized patients, the transition from hospital to home is frequently accompanied by a significant amount of information to absorb. The objective of this work was to engage patients, caregivers, and healthcare providers in codeveloping patient-oriented discharge instructions, (ie, a brief transition plan with information that patients want). Overseen by a multidisciplinary advisory team, a participatory action approach using mixed methods was employed.

Innovators and early adopters of population health in healthcare: real and present opportunities for healthcare-public health collaboration.

The population health approach - which has long been a cornerstone ideology for those in public health - is increasingly embraced by various actors in the healthcare sector, including but not limited to those in primary healthcare. There is much to be gained from public health's involvement in these early efforts, which could enable the pursuit of approaches that integrate both individual- and population-level interventions. These collaborative efforts could serve as the initial building blocks for transformative change, provided that others follow suit.