Screening of Pathogenic Missense Single Nucleotide Variants From Gene Associated With the Hepatocellular Carcinoma: An Approach.

gene encodes a phospholysine phosphohistidine inorganic pyrophosphate phosphatase, which functions as a tumor-suppressor protein. The tumor suppression by this protein has been confirmed in various cancers, including hepatocellular carcinoma (HCC). downregulation promotes cell growth and proliferation by modulating the signaling pathway.