Complexation of ibuprofen with water soluble p-sulfonatocalix [4]arene: A potential candidate for drug delivery applicatio.

Complexation of ibuprofen with water soluble p-sulfonatocalix[4]arene (3) was evaluated. Both molecules exhibit a host and guest type complexation. pH, complex stoichiometry and binding constant were determined by UV-Vis and FT-IR spectroscopy.