Development of a Highly Hydrophobic Micro/Nanostructured Nanocomposite Coating of PLA-PEG-Cloisite 20A Nanoclay with Excellent Hemocompatibility and Rapid Endothelialization Properties for Cardiovascular Applications.

Despite the unique properties of clay nanocomposites for cardiovascular applications, there are few data on the hemocompatibility of these nanomaterials. This study represents the first comprehensive investigation of the hemo/biocompatibility of clay nanocomposites . Nanocomposite coatings of polylactic acid (PLA)-polyethylene glycol (3 wt %)-Cloisite20A nanoclay (3 wt %) were produced using electrospraying technique as potential drug-eluting stent (DES) coatings.

Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?

Background: Hemoglobin J is one of the fast hemoglobin that has a more negative charge due to β77His→Asp substitution. Acquisition of this hemoglobin is not associated with any specific clinical sign, but the combination of this hemoglobinopathy with beta-thalassemia and other hemoglobinopathies can cause challenges.

Case Presentation: In this article, two cases with hemoglobin J are introduced; the first patient for premarital testing and the other for his fatigue.

Role of platelet-derived microparticles in transfer of the chemokine receptor CXCR4 to CXCR4-negative cells.

Membrane-derived microparticles (PMPs) are produced from platelets during activation, storage, and apoptosis. PMP can transfer some adhesion molecules such as CXCR4 to CXCR4-negative cells. In this study, the ability of PMPs to deliver CXCR4 molecule to CXCR4-null targets (Daudi, K562 and U937 cell line) was evaluated and the different concentrations of PMPs were examined to transfer CXCR4.