Efficacy of Crocus sativus (saffron) in treatment of major depressive disorder associated with post-menopausal hot flashes: a double-blind, randomized, placebo-controlled trial.

Purpose: Due to concerns regarding the side effects of hormone therapy, many studies have focused on the development of non-hormonal agents for treatment of hot flashes. The aim of this study was to evaluate the efficacy and safety of saffron (stigma of Crocus sativus) in treatment of major depressive disorder associated with post-menopausal hot flashes.

Methods: Sixty women with post-menopausal hot flashes participated in this study.

Comparing dietary patterns of depressed patients versus healthy people in a case control protocol.

Introduction: Major depressive disorder is the leading cause of disability around the world. Because of the high rate of medication discontinuation by patients and the risk of recurrence, factors such as nutrition could be useful for the prevention or treatment of depression. The relationship between depression and dietary patterns has been reported in a few studies but with controversial results.

Pfannenstiel versus Maylard incision for gynecologic surgery: a randomized, double-blind controlled trial.

Objective: The aim of this study was to compare the effects of the transverse muscle-cutting Maylard incision and the Pfannenstiel incision for hysterectomies, in terms of postoperative complications, pain, and quality of life.

Materials And Methods: This randomized, double-blind study compared two laparotomy techniques. All hysterectomies were performed for benign conditions.