Perspective of placenta derived mesenchymal stem cells in acute liver failure.

Acute Liver failure (ALF) is a life-threatening disease and is determined by coagulopathy (with INR ≥ 1.5) and hepatic encephalopathy as a result of severe liver injury in patients without preexisting liver disease. Since there are problems with liver transplantation including lack of donors, use of immunosuppressive drugs, and high costs of this process, new therapeutic approaches alongside current treatments are needed.

A novel method for near-infrared fluorescence imaging of the urethra during perineal and transanal surgery: demonstration in a cadaveric model.

Aim: Transanal total mesorectal excision is a promising novel sphincter-saving procedure for low rectal cancer. However, the transanal bottom-up dissection is associated with increased rates of iatrogenic urethral injuries. Near-infrared fluorescence (NIRF) imaging, given its deeper tissue penetration, has been explored in a limited number of studies for enhanced intra-operative urethral visualization.

Adamantinomatous Craniopharyngioma in an Adult: A Case Report with NGS Analysis.

Purpose: Several recent studies have documented and mutations which are mutually exclusive for adamantinomatous craniopharyngioma (ACP) and papillary craniopharyngioma (PCP) tumors. This discovery is helpful in the development of novel targeted therapies in successful clinical trials with mutations in PCP cases. However, no such targeted therapy is available yet for ACP.

A hierarchical 3D camellia-like molybdenum tungsten disulfide architectures for the determination of morphine and tramadol.

A practical technique was applied to fabricate MoWS nanocomposite through a one-pot hydrothermal method for use as the electrocatalyst. The characterization of MoWS nanocomposite was investigated by several techniques to identify the size, crystal structure, and elemental composition. MoWS nanocomposite exhibited a unique and well-defined hierarchical structure with neatly and densely piled nanopetals acting as the active sites in the electrocatalytic reactions.

Hyperspectral enhanced reality (HYPER) for anatomical liver resection.

Background: Clinical evaluation of the demarcation line separating ischemic from non-ischemic liver parenchyma may be challenging. Hyperspectral imaging (HSI) is a noninvasive imaging modality, which combines a camera with a spectroscope and allows quantitative imaging of tissue oxygenation. Our group developed a software to overlay HSI images onto the operative field, obtaining HSI-based enhanced reality (HYPER).

Morphological Redescriptions and Molecular Phylogeny of Three Stentor Species (Ciliophora: Heterotrichea: Stentoridae) from Korea.

The morphologies of the three freshwater stentorid ciliates in Korea, Stentor coeruleus (Pallas, 1766); Stentor muelleri Ehrenberg, 1831, and Stentor tartari Murthy Bai, 1974, were investigated based on live observations and protargol impregnation. The Korean population of S. tartari exhibits the following characteristics: body size 200-355 × 85-135 µm in vivo, 62-106 somatic kineties, 8-13 peristomial kineties, 110-180 adoral membranelles, mostly two macronuclear nodules and 5-18 micronuclei, reddish and colorless cortical granules and the presence of symbiotic algae.

Data on systematic review and meta-analysis of epidemiologic evidence on the association between perineal use of talc powder and risk of ovarian cancer.

This paper describes data from a systematic review and meta-analysis [1] conducted to identify and evaluate published peer reviewed evidence on the association between perineal use of talc powder and risk of ovarian cancer. These data were collected from multiple electronic bibliographic databases, as well as from grey literature sources, without applying time, language or other filters. A meta-analysis was conducted to quantitatively assess the ovarian cancer risk in relation to talc use and other potential risk factors.

Broadband absorption of nanostructured stainless steel surface fabricated by nanosecond laser irradiation.

Highly efficient broadband absorbing surfaces covering the UV, visible and near-IR regions are of great importance for low-light imaging devices, optical devices and optoelectronic devices. In this work, we demonstrate the fabrication of remarkably efficient absorbing surfaces due to the formation of nanoflower-like cavity structures on a stainless steel (SS304) surface, along with micropatterning in a hierarchical fashion. The fabrication process is carried out using noncontact, programmable, single-step laser irradiation by an inexpensive and robust 532 nm nanosecond laser.

Effect of Ambient Temperature Changes on Blood Flow in Anterior Cerebral Artery of Patients with Skull Prosthesis.

Background: In many cases, an injury to the head leads to the replacement of a part of the skull with materials such as titanium and polyether ether ketone.

Methods: Three-dimensional heads model of 15 healthy individuals and 13 patients were prepared. The models were simulated using thermal fluid structure interaction analysis to evaluate the effects of cold (5°C) and hot (55°C) temperatures of the skull on the conditions of blood flow in the anterior cerebral artery.

Fluorescence detection of laccases activity by the photoinduced electron transfer (PET) process.

Laccases play a vital role in some physiological processes, for example in morphogenesis, carbon cycle, and defense against parasitism. So, designing a high-sensitivity accurate method is essential for researchers. In this study, a simple fluorescence method based on the function of carbon nitride (g-CN) by dopamine is synthesized.

Facile synthesis and characterization of magnetic nanocomposite ZnO/CoFeO hetero-structure for rapid photocatalytic degradation of imidacloprid.

This work has attempted to investigate the potential of ZnO/CoFeO magnetic nanocomposite to mineralize imidacloprid completely to have sustainable pollutant free and safe water supply. The co-precipitation method was performed to prepare the composites; was performed to characterize composites, scanning electron microscope (SEM), transmission electron microscopy (TEM), energy dispersive x-ray crystallography (EDX), x-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, and vibrating sample magnetometer (VSM). It was attempted to explore and enhance parameters influencing the process and the percentage of imidacloprid degradation, including photocatalyst amount, pesticide concentration, pH, radiation time, and temperature.

Coincidence of Concha Bullosa with Nasal Septal Deviation; Radiological Study.

Concha bullosa (CB) is the most common sinonasal anatomical variation reported in literature, it occurs most often in the middle turbinate. Causes of development are not clearly identified but coincident prevalence with deviated nasal septum (DS) is common. To study the relationship between DS and development of CB A prospective study including 40 patients with DS, CT scans were thoroughly analyzed to detect the presence of CB, its type, and laterality.

Coblation Versus Conventional Tonsillectomy: A Double Blind Randomized Controlled Trial.

Post tonsillectomy bleeding and pain are two main problems following traditional tonsillectomy. Coblation therapy (controlled ablation) was first used in tonsillectomy in 2001. A great amount of literature debated around its use with controversial opinions regarding its benefits, efficacy, and cost.

Molecular Dynamics Simulation Reveals Exposed Residues in the Ligand-Binding Domain of the Low-Density Lipoprotein Receptor that Interacts with Vesicular Stomatitis Virus-G Envelope.

Familial hypercholesterolemia (FH) is an autosomal dominant disease most often caused by mutations in the low-density lipoprotein receptor (LDLR) gene, which consists of 18 exons spanning 45 kb and codes for a precursor protein of 860 amino acids. Mutations in the LDLR gene lead to a reduced hepatic clearance of LDL as well as a high risk of coronary artery disease (CAD) and sudden cardiac death (SCD). Recently, LDLR transgenes have generated interest as potential therapeutic agents.

Primary Anorectal Amelanotic Melanoma: The First Case Report from Saudi Arabia.

Anorectal melanomas are exceptionally uncommon and only 30% of anorectal melanomas are amelanotic. We report here a case of an anorectal amelanotic melanoma in a female patient. An 84-year-old patient complained of anal mass for 3 months.

Next generation DNA sequencing of atypical choroid plexus papilloma of brain: Identification of novel mutations in a female patient by Ion Proton.

Choroid plexus papilloma (CPP) is a rare benign tumor of the central nervous system that is usually confined to the cerebral ventricles. According to the World Health Organization, CPP corresponds to a grade I atypical CPP (a-CPP); however, it can become more aggressive and reach grade II, which can rarely undergo malignant transformation into a choroid plexus carcinoma (grade III). To the best of our knowledge, identification of these tumors mutations by next generation DNA sequencing (NGS) has not been yet reported.

anxiolytic and anti-inflammatory activities of water-soluble extract (WSE) of (L.) seeds.

The WSE is a highly polar, gummy and mucilaginous bioactive content of the (L.) seeds. This study reports the anxiolytic and anti-inflammatory effects of WSE investigated using Elevated Plus Maze (EPM) and Hole-Board Test (HBT) in adult mice and human RBCs haemolysis inhibition and protein denaturation respectively.

The effect of presence of family members on the anxiety level of candidates for esophagogastroduodenoscopy: A randomized controlled trial.

Anxiety and its control is a public health problem worldwide. This study was conducted to determine the effect of family members' presence on the anxiety level of patients who were candidates for esophagogastroduodenoscopy (EGD). This randomized controlled trial study was performed in Shahid Chamran hospital in city of Saveh in IR Iran.

Pharmacological properties of Centella asiatica hydrogel in accelerating wound healing in rabbits.

Background: Various extracts of Centella asiatica (Apiaceae) and its active constituent, asiaticoside, have been reported to possess wound healing property when assessed using various in vivo and in vitro models. In an attempt to develop a formulation with accelerated wound healing effect, the present study was performed to examine in vivo efficacy of asiaticoside-rich hydrogel formulation in rabbits.

Methods: Asiaticoside-rich fraction was prepared from C.

A Faith-Based Intervention to Reduce Blood Pressure in Underserved Metropolitan New York Immigrant Communities.

Minority populations, including Asian Americans, face disparities in hypertension compared with non-Hispanic whites. This underscores the need for culturally adapted programs in settings that reach Asian American communities, such as faith-based organizations. We worked collaboratively with community partners to culturally adapt and implement an evidence-based community blood pressure monitoring program for Asian Americans (Asian Indians, Koreans, Filipinos, and Bangladeshis) in metropolitan New York during 2015 and 2016.

Optimization of Aceclofenac Proniosomes by Using Different Carriers, Part 1: Development and Characterization.

In the contemporary medical model world, the proniosomal system has been serving as a new drug delivery system that is considered to significantly enhance the bioavailability of drugs with low water solubility. The application of this system can improve the bioavailability of aceclofenac that is used for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. The present study is intended to develop an optimized proniosomal aceclofenac formula by the use of different carriers.

Simultaneous voltammetric determination of glutathione, doxorubicin and tyrosine based on the electrocatalytic effect of a nickel(II) complex and of Pt:Co nanoparticles as a conductive mediator.

Glutathione (GSH) is an important tripeptide that plays an important role in preventing damage to reactive oxygen species. An electrochemical assay was fabricated for this purpose by modification of a carbon paste electrode (CPE) with bis(1,10-phenanthroline)(1,10-phenanthroline-5,6-dione)nickel(II) hexafluorophosphate (BPPDNi) as new electro-catalyst and Pt:Co nanoparticle (Pt:CO-NPs) as highly conductive mediator. The analyses were performed at a scan rate of 10 mV/s and at a pH value of 7.

Effects of mineral trioxide aggregate, calcium hydroxide, biodentine and Emdogain on osteogenesis, Odontogenesis, angiogenesis and cell viability of dental pulp stem cells.

Background: Vital pulp therapy preserves and maintains the integrity and the health of dental pulp tissue that has been injured by trauma, caries or restorative procedures. The enhancement of cells viability and formation of reparative dentine and new blood vessels are vital determinants of the success of direct pulp capping. Therefore, the aims of this study was to evaluate and compare the in vitro osteogenic, odontogenic and angiogenic effects of mineral trioxide aggregate (MTA), calcium hydroxide [Ca(OH)], Biodentine and Emdogain on dental pulp stem cells (DPSCs) and examine the effects of the tested materials on cell viability.

Influence of organizational and social contexts on the implementation of culturally adapted hypertension control programs in Asian American-serving grocery stores, restaurants, and faith-based community sites: a qualitative study.

Hypertension affects a third of U.S. adults and is especially high among Asian American groups.

Whole exome sequencing detects novel variants in Saudi children diagnosed with eczema.

Background: Eczema is also known as atopic dermatitis is well-known for the skin disease globally. In Saudi Arabia, exome sequencing studies have not been documented. The purpose of this study was to scrutinize the disease causing mutations in children affected with eczema with exome sequencing in the Saudi population.