F-FDG PET/CT versus bone marrow biopsy in detecting bone marrow infiltration in initial staging of pediatric lymphoma.

Background: To evaluate the efficacy of PET/CT usingF-FDG (F-fluorodeoxyglucose) as a radiotracer compared to conventional bone marrow biopsy (BMB) in detecting infiltration to bone marrow (BM) in pediatric patients with lymphoma at the time of initial diagnosis.

Methods: 66 pediatric patients with lymphoma (47Hodgkin's and 19non-Hodgkin's lymphoma) were referred for initial staging byF-FDG PET/CT study. All patients underwent bilateral iliac BMB and F-FDG PET/CT scan with no more than 2 weeks interval in-between.

Volumetric parameters of the primary tumor and whole-body tumor burden derived from baseline F-FDG PET/CT can predict overall survival in non-small cell lung cancer patients: initial results from a single institution.

Background: Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are volumetric parameters derived from F-FDG PET/CT, suggested to have a prognostic value in cancer patients. Our study aimed to test whether these volumetric parameters of the primary tumor and whole-body tumor burden (WBTB) can predict overall survival (OS) in non-small cell lung cancer (NSCLC) patients.

Materials And Methods: Thirty biopsy-proven NSCLC patients who had not begun anti-tumor therapy were included in this prospective study.