Molecular diagnostics offer a personalized and cost-effective approach for treating infectious diseases and cancer, utilizing techniques like rolling circle amplification (RCA) for precise identification of nucleic acids.
Superparamagnetic microspheres, particularly the newly developed streptavidin-modified magnetic poly(2-hydroxyethyl methacrylate) (STV-mag.PHEMA), show promise for efficient multi-step protocols in molecular assays despite showing lower binding efficiency in comparison to traditional methods.
Ongoing research aims to optimize these microspheres and assess their effectiveness against similar-sized particles, potentially enhancing their application in clinical diagnostics.