Publications by authors named "Taekyung Han"
The Role of Leptin in the Association between Obesity and Psoriasis.
Biomol Ther (Seoul)
January 2021
Adipose tissue secretes many adipokines which contribute to various metabolic processes, such as blood pressure, glucose homeostasis, inflammation and angiogenesis. The biology of adipose tissue in an obese individual is abnormally altered in a manner that increases the body's vulnerability to immune diseases, such as psoriasis. Psoriasis is considered a chronic inflammatory skin disease which is closely associated with being overweight and obese.
View Article and Find Full Text PDFObjectives: Asians (including Chinese, Japanese and Koreans), who generally have a relatively smaller body size and a lower mean body mass index (BMI), have a relatively higher risk of developing android-type obesity than westerners. Substitution of alanine for threonine (Ala54Thr) on the FABP2 gene (rs 1799883) is related to insulin resistance and obesity. However, few studies have examined this substitution in Koreans, and the number of Korean subjects in those studies is limited.
View Article and Find Full Text PDFArticle Synopsis
- - The study examined how regular treadmill exercise could counteract cognitive issues caused by a high-fat diet (HFD) in mice, specifically focusing on memory linked to the hippocampus.
- - Results showed that the exercise helped reduce weight gain and liver triglyceride levels associated with the HFD, while also improving memory performance in water maze tests and enhancing neurogenesis markers in the brain.
- - Additionally, exercise led to reduced inflammation, oxidative stress, and cell death in the hippocampus, suggesting that regular physical activity could be an effective way to mitigate HFD-induced memory problems through various protective mechanisms.
Article Synopsis
- Researchers studied how exercise helps reduce depression caused by stress in female mice that had their ovaries removed.
- They found that stressed mice showed more immobility, but those that exercised regularly or took a certain medication felt better.
- The study showed that exercise and medication could restore brain health markers affected by stress, suggesting that both stress and low hormone levels contribute to depression in these mice.
Purpose: This study examined the relations of serum vitamin D levels to body fatness, cardiorespiratory fitness (CRF), and metabolic risk factors in young adults in Korea.
Methods: Between 2007 and 2009, 799 young men completed a health examination. Body fatness, CRF based on a maximal treadmill exercise test, and measurements of metabolic risk factors were measured in study participants.
Relationship of PGC-1α gene polymorphism with insulin resistance syndrome in Korean children.
Asia Pac J Public Health
March 2015
This study aimed to investigate the associations between peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) gene Gly482Ser polymorphism (rs8192678) and parameters of insulin resistance in a sample of Korean children. A total of 286 children aged 10 to 12 years old were recruited from local elementary schools. Measured variables included body fat, blood pressures, blood lipids, glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), and accelerometer-based physical activity (PA).
View Article and Find Full Text PDFLittle information is available regarding how body fatness and cardio/respiratory fitness (CRF) are associated with serum vaspin. The purpose of the study was to investigate the combined effect of body mass index (BMI) and CRF on serum vaspin in Korean young men. In a cross-sectional study, we examined 490 Korean young men (mean age 23.
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