Publications by authors named "Tadros Atalla"
Histopathology
February 2022
Article Synopsis
- Basal-like breast cancer is a challenging subtype that often occurs in younger patients, is difficult to treat due to lack of standard hormone receptors, and is characterized by specific gene expressions, including SOX10.*
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- The study investigated how well SOX10 indicates the basal-like subtype compared to other markers like CK5 and EGFR, using immunohistochemical staining and a PAM50 gene expression analysis on a set of breast cancer tissue samples.*
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- Results showed SOX10 had a high specificity (98.1%) and decent sensitivity (70.9%) for identifying basal-like cancers, making it a valuable biomarker that works well regardless of hormone receptor status.*
