Publications by authors named "Tadesse G"

Background: Individuals, who suffer from severe mental illnesses (SMI), such as bipolar disorder (BD), schizophrenia (SCZ), and major depressive disorder (MDD), are more likely to engage in risky sexual behavior. A severe mental illness can lead to a decrease in impulse control, a reduction in cognitive function and memory, and a psychosocial impairment that increases risky sexual behavior. Risky sexual behavior (RSB) can lead to health problems such as sexually transmitted infections, including HIV/AIDS, early pregnancy, and unplanned pregnancies.

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Background: Depression and anxiety are the most common types of mental disorders among cancer patients. Many research studies carried out in African countries indicate that anxiety and depression are highly prevalent, but the results vary across regions. Thus, this study aimed to estimate the pooled prevalence and associated factors of depression and anxiety among cancer patients in Africa.

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Background: The development of community-based health insurance (CBHI) was driven by the need to provide economic protection for the poor against unexpected healthcare expenses. This can lead to increased patient satisfaction with their overall care. Maintaining high levels of client satisfaction with pharmacy services is crucial for effectively treating patients with psychiatric disorders.

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Background: Perinatal depression is a significant public health issue affecting one in four women globally. It occurs at a critical time of a woman's life; affecting her relationships with family, and child's emotional, behavioral, and cognitive development. Considering the burden of the problem to the whole family, this systematic review and meta-analysis was conducted to estimate the pooled prevalence of perinatal depression and its determinants in Ethiopia to provide up-to-date evidence at a national level.

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Background: The occurrence of potential drug‒drug interactions (pDDIs) is a serious global issue that affects all age groups, with the elderly population being the most vulnerable. This is due to their relatively high rates of comorbidity and polypharmacy, as well as physiological changes that can increase the potential for DDIs and the likelihood of adverse drug reactions. The aim of this study was to estimate the prevalence of pDDIs and associated factors among elderly patients in Ethiopia.

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Background: Caring for people with mental illness requires a significant investment of personal physical, mental, social, and financial resources, which greatly impact the daily lives of caregivers. The process of providing care is multifaceted and intricate, involving both positive and negative emotional responses. Burden of care is a term used to describe the negative effects of caregivers' burden on their physical, psychological, social, and economic well-being.

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Background: Seventy percent of epileptic patients may not experience seizures if they receive proper treatment with antiepileptic drugs (AEDs). However, many children and adolescents face poor seizure control (PSC). Therefore, the purpose of this review is to systematically and quantitatively summarize the pooled prevalence of PSC and its predictors among children with epilepsy in Ethiopia.

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Background: Optimal medication adherence is vital for the successful implementation of highly active antiretroviral therapy (HAART) in managing HIV infection. Global efforts aim to minimize the burden of antimicrobial resistance (AMR), including HIV-associated drug resistance.

Methods: This systematic review and meta-analysis followed PRISMA guidelines and searched multiple databases for eligible studies published until July 10, 2023.

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Article Synopsis
  • HIV-related stigma significantly affects people living with HIV/AIDS, leading to psychological distress, reduced quality of life, and reluctance to seek treatment or disclose their status.
  • In a comprehensive review of studies involving over 50,000 individuals, the pooled prevalence rates of perceived stigma and internalized stigma were found to be 41.23% and 35.68%, respectively, with Nigeria and Ethiopia showing the highest rates for perceived stigma.
  • The findings suggest that women and those living in rural areas are at a greater risk of experiencing stigma, highlighting the need for targeted interventions to address this issue among these vulnerable populations.
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  • - The study focused on the high prevalence of gender-based violence (GBV) among refugees and internally displaced women in Africa, finding that nearly 48.2% faced such violence during emergencies.
  • - Researchers analyzed 17 studies involving over 6,000 women, utilizing various databases and statistical methods to assess the magnitude and contributing factors of GBV, identifying young age, alcohol consumption, and lack of social protection as significant risk factors.
  • - The findings highlight a critical public health issue, suggesting that interventions must focus on protecting vulnerable groups, especially younger women and those without social support in humanitarian settings.
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  • - This study investigates how vaccination status affects RT-PCR cycle threshold (Ct) values in suspected COVID-19 cases, comparing results from rapid diagnostic tests (RDT) and RT-PCR testing.
  • - Among 453 suspected cases, RDT showed 65.8% positive and RT-PCR showed 64.2% positive results, indicating discrepancies between the two testing methods.
  • - The findings suggest that vaccination status has little influence on viral load as indicated by Ct values, complicating the interpretation of tests for vaccinated individuals, particularly in cases of breakthrough infections.
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Background: Stroke is a leading cause of death and disability worldwide. While caregivers play a vital role in recovery, their long-term support can affect their mental well-being. This study aims to estimate the pooled prevalence of depression and associated factors among caregivers of stroke survivors in developing countries.

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Background: The life-threatening diseases known as ACS (acute coronary syndrome) continue to produce considerable rates of morbidity and mortality despite breakthroughs in therapy. The study determined clinical outcome and its predictors in patients at the University of Gondar Comprehensive and Specialized Hospital (UOGCSH), North West Ethiopia.

Design, Setting, And Participants: A retrospective cohort study design was employed at UOGCSH from January 31, 2018 to February 1, 2023.

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Background: Antisocial personality disorder (ASPD) is a common mental health condition with major public health consequences, affecting 0.2-3.3 % of the general population.

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Article Synopsis
  • Many adolescent females in Ethiopia are at high risk of gender-based violence (GBV), yet there is limited data addressing the issue specifically among female students in higher educational institutions.
  • The study analyzed existing research using multiple databases to determine the extent of GBV and its contributing factors, including childhood experiences and social behaviors, employing statistical techniques for accuracy.
  • Results indicated that over half of the female students experienced GBV, with strong links to factors like witnessing domestic abuse, family communication issues, and peer influences, highlighting the need for better support and preventative measures in educational settings.
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Background: A large number of people are often directly involved in armed conflict and, therefore, are at greater risk of developing a wide range of mental disorders, including post-traumatic stress disorder. Despite this, few have been reported about it in low- and middle-income countries, including Ethiopia.

Objective: This study was carried out to assess the magnitude and factors associated with post-traumatic stress disorder among war-affected internally displaced people in northwest Ethiopia, 2022.

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Background: Sexual dysfunction is the most frequent health problem among psychiatric patients. This could be the result of both the nature of the illness itself and the side effects of prescribed psychotropic medications. It also significantly affects an individual's general well-being, interpersonal relationships, self-esteem, and treatment outcomes.

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Background: Adolescent mental health issues are emerging as a significant public health concern across many low- and middle-income countries, particularly in Africa. This study aims to evaluate the aggregated prevalence and contributing risk factors of mental health distress among adolescents in Africa.

Methodology: A comprehensive search of PubMed, PsycINFO, Web of Science, Google Scholar, and HINARI databases was conducted to identify relevant articles on the prevalence and risk factors associated with mental health distress among African adolescents, published up to December 2023.

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Background: Premenstrual dysphoric disorder (PMDD) is the most prevalent but neglected psychiatric disorder, with somatic symptoms that are severe enough to markedly affect usual daily activities and have a negative impact on mental health and quality of life by affecting female patients' behavior and cognition. Studies regarding premenstrual dysphoric disorder and associated factors among high school students in low- and middle-income countries are limited. Therefore, the aim of this study was to assess the prevalence and associated factors of PMDD among high school students, and this is pivotal in further investigation.

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Background: Poor sleep quality is a serious concern among diabetes mellitus patients, adversely affecting glycemic management and the prognosis of diabetic patients. Therefore, the main aim of this study was to estimate the overall pooled prevalence of poor sleep quality and its associated factors among diabetic patients in Sub-Saharan Africa.

Methods: Several search databases were employed to retrieve the eligible studies.

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Background: Epilepsy is a global health and economic burden with major problems that have an impact on physical, psychological, and social activities. Quality of life (QoL) is often disturbed and can be influenced by many factors, like anti-seizure medication side effects, the sociocultural environment, and various disease-related factors. The aim of this systematic review and meta-analysis is to provide an overview of the most recent information available regarding the pooled prevalence of poor quality of life and associated factors among adult people with epilepsy in Ethiopia.

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Objectives: The objective of this study is to estimate the overall pooled prevalence of depression and its associated factors among high school, college and university students in Ethiopia.

Design: Systematic review and meta-analysis.

Data Sources: PubMed/MEDLINE, EMBASE, Science Direct, African Journal Online and Google Scholar.

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Background: Post-traumatic stress disorder (PTSD) is a significant mental health concern globally, particularly prevalent in populations exposed to war and conflict. This systematic review and meta-analysis aim to examine the prevalence and factors associated with PTSD among the Ethiopian population residing in war-affected communities.

Methods: The review was reported according to the PRISMA guidelines.

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