Publications by authors named "Tadashi Onishi"

Article Synopsis
  • - Hypertrophic pulmonary osteoarthropathy (HPO) is characterized by clubbed fingers, bone growth in long bones, and arthritis, often linked to lung cancers like adenocarcinoma or squamous cell carcinoma.
  • - A case study described a 47-year-old woman with HPO alongside a diagnosis of non-small cell lung cancer, who underwent surgery (right upper lobectomy) that relieved her joint symptoms.
  • - The patient developed a brain metastasis a year after surgery but showed no recurrence of HPO, indicating that treating the lung cancer can improve joint symptoms associated with HPO.
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Article Synopsis
  • A 50-year-old woman was diagnosed with a neuroendocrine tumor (NET) in the lower rectum after a colonoscopy revealed a 15 mm tumor, and biopsy confirmed its low proliferation index (Ki-67 <1%).
  • Imaging showed no distant metastasis, but the tumor's size and proximity to the anal margin made endoscopic resection less advisable, leading to a decision for surgical resection.
  • Following a laparoscopic rectal intersphincteric resection and upper D2 dissection, pathology revealed the tumor had invaded the submucosa with lymph node metastasis, but the patient recovered well and has had no recurrence after one year.
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To elucidate ideal strategy of treatment for advanced lower rectal cancer, we investigated 11 patients with clinically suspected lateral pelvic node(LPN)metastasis among 36 patients who received neoadjuvant chemoradiation therapy(NCRT). Nodal metastasis was diagnosed as positive when the major axis of a lymph node was over 7mm in computed tomography(CT). Both tumor and nodal downstaging were observed in CT after NCRT; pathological complete response and ypN0 was obtained in 2(18.

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A therapeutic guideline for sigmoid volvulus (SV) has not been established, and the most recommended surgical procedure for SV has not been determined. Our objective is to assess the usability of elective laparoscopic sigmoidectomy and the feasibility of single-incision laparoscopic surgery for SV following endoscopic reduction. SV typically affects the elderly and accounts for 1% to 7% of intestinal obstructions in Western countries.

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Small bowel cancer is relatively rare among gastrointestinal tract cancers, including esophageal, gastric and colorectal cancers. The majority of cases of small bowel cancer are diagnosed at an advanced stage, resulting in poor outcomes. The clinical effects of chemotherapy on small bowel cancer have been investigated in a limited number of studies from Europe and the USA.

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Twenty patients( 30 nodules) with metastatic liver cancer( MLC) and 10 cases with hepatocellular carcinoma( HCC) treated by stereotactic radiotherapy (SRT) were analyzed. SRT was administered at 48.0 or 52.

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Background: In this retrospective study, we investigated the clinical outcomes of endoscopic gastroduodenal stenting (EGDS) for gastric outlet obstruction( GOO) caused by unresectable gastric cancer( UGC).

Methods: A retrospective study was performed on 20 UGC patients with GOO between 2007 and 2012. We compared the clinical outcomes of EGDS using the WallFlex stent( GDS group, n=8) and palliative Roux-en-Y gastrojejunostomy( RYGJ group, n=12).

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Twenty cases (27 therapeutic sites/30 nodules) of metastatic liver cancer treated with stereotactic radiotherapy (SRT)were analyzed. The original sites of cancer were colorectal(8 cases), breast(4 cases), stomach(3 cases), esophagus(2 cases), and other organs (3 cases). SRT was performed with 52.

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A 75-year-old man was diagnosed as gall bladder carcinoma by postoperative histological examination following laparoscopic cholecystectomy. He underwent the second surgery of resection of liver bed and port sites with lymph node dissection. Isolated hepatic metastasis of 20 mm in diameter was found in S4/8 by MRI 18 months postoperatively, and stereotactic radiotherapy (52.

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Background: In our hospital, the starting dose of S-1 for patients over 75 years of age with advanced gastric cancer was determined by body surface of area, creatinine clearance, performance status(PS)and the presence of complications. The objective of this retrospective study was to investigate the proper administration of S-1 in elderly patients by comparing patients given a standard dose of S-1 to those given a reduced dose.

Methods: Twenty patients participated.

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