[Complete response to treatment with hepatic arterial infusion of cisplatin powder (IA-call) in a case of hepatocellular carcinoma with multiple lung metastases].

A 74-year-old woman was admitted to our hospital to treat her hepatocellular carcinoma (stage IVB) with multiple lung metastases. She was treated with 3 times of hepatic arterial infusion of cisplatin powder (IA-call). After the treatment, liver mass and lung tumors were disappeared and high levels of tumor markers (AFP and PIVKA-II) were markedly decreased.

Helicobacter pylori infection prevents nocturnal gastric acid breakthrough.

Background/aims: Nocturnal gastric acid breakthrough (NAB) is given attention as one of the factors that cause refractory reflux esophagitis. However, its clinical states and mechanisms are not yet clearly understood. We studied whether there will be a NAB outbreak or not among healthy Japanese male volunteers upon administration of omeprazole, as well as what kind of factors will be involved in case of an outbreak.