Publications by authors named "Tacio Luis Cavalcante Coradine"
Genetic Epidemiology and Clinical Characteristics of Patients with Spinocerebellar Ataxias in an Unexplored Brazilian State, Using Strategies for Resource-Limited Settings.
Cerebellum
April 2024
Spinocerebellar ataxias (SCAs) have a worldwide average prevalence of 2.7 cases per 100,000 individuals, with significant geographic variability. This study aimed to develop resource-limited strategies to detect and characterize the frequency and genetic-clinical profile of SCAs in an unexplored population from Alagoas State, a low Human Development Index state in northeastern Brazil.
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- - A 56-year-old woman experienced worsening weakness in her legs and abnormal sensory/autonomic symptoms 21 years after receiving a kidney transplant, where she was on immunosuppressive medication.
- - MRI scans revealed spinal and brain abnormalities, while cerebrospinal fluid analysis indicated low glucose levels and positive results for Epstein-Barr virus, but her condition deteriorated despite treatment.
- - The final diagnosis was myeloradiculopathy due to a post-transplant lymphoproliferative disorder, classifying it as a type of lymphoma, with a discussion on its clinical features, diagnosis, and management strategies.
Spontaneous intracranial hypotension: from cerebral venous thrombosis to neurosurgical treatment: a case series experience from a Brazilian tertiary health care center.
Arq Neuropsiquiatr
February 2023
Background: Spontaneous intracranial hypotension (SIH) is a secondary cause of headache and an underdiagnosed disease. The clinical presentation can be highly variable. It typically presents with isolated classic orthostatic headache complaints, but patients can develop significant complications such as cerebral venous thrombosis (CVT).
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