THE ROLE OF INSULIN-LIKE GROWTH FACTOR-1 AND INSULIN IN DEVELOPMENT OF COLORECTAL CANCER.

The study's goal is to discover the function of the IGF-1 factor and insulin in the development of colorectal cancer. Changes in these factors should be explored at various phases of colorectal cancer, including the preoperative and postoperative periods. 38 patients were selected for the study.

ACTION OF SIMVASTATIN IN IMPROVING COGNITIVE FUNCTIONS IN VASCULAR DEMENTIA.

The purpose of this study was to determine the efficacy and safety of statins in improving cognitive function in patients with vascular dementia. As the most important etiological factors of the disease are atherosclerotic vascular lesions, one of the important areas of treatment is lipid metabolism analysis and drug treatment for dyslipidemia. 31 patients were selected for the study, ages 65-65 years, 18 males, 13 females.

FACTORS ASSOCIATED WITH DECLINE OF FEV1 IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

The purpose of the study was to search for a correlation between FEV1 and the possible predictors that determine disease progression and lung function deterioration in COPD patients. The research was conducted at N. Kipshidze Central University Clinic.

RISK FACTORS ASSOCIATED WITH THE SEVERITY OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

The purpose of the study was to reveal possible predictors that are associated with progression of chronic obstructive pulmonary disease (COPD) and deterioration of lung function in COPD patients. The research was conducted at N. Kipshidze Central University Clinic.

[THE COMBINED THERAPY IN HYPERTENSIVE PATIENTS WITH DYSLIPIDEMIA].

Purpose - studying of clinical efficiensy of the combined therapy (Amlodipin with Valsartan and fibrates) in hypertensive patients with dyslipidemia. Were studied 58 patients (40-65 years old) with hypertension (the level of arterial pressure was ≥140/90 and ≤180/110mm.Hg.

[Influence of the soybean flavonoid supplement on the synthesis of nitric oxide (NO) in the patients with atherosclerosis].

66 patients of 40-77 age group with atherosclerosis were studied. The observation period made up 4 weeks. The patients were divided into two groups.

[Various biochemical mechanisms of the combined action of extreme factors].

Biologically active substances exhibiting the radioprotective effect were formed in liver tissue after treatment with hypoxia and with electromagnetic irradiation of ultrahigh frequency. The protective factor was found to be among protein or peptide fractions. Possible mechanisms of formation and action of the biologically active substance are discussed.

[Possible mechanisms of the radiomodifying action of exogenous hypoxia and electromagnetic radiation in the SHF range].

It was shown that biologically active substances formed in the liver tissue under the effect of hypoxia and SHF electromagnetic radiation produce a radioprotective effect when administered 15 min before exposure and have no protective effect when administered after irradiation.