[Effect of small-doses ketamine on postoperative pain management with combinations morphine/ketoprofen or lidol/ketoprofen after major gynecological surgery] [corrected].

We examine the potential beneficial effect of small-doses ketamine on postoperative pain management with combinations morphine/ketoprofen or lidol/ketoprofen after major gynecological surgery. After patient written consent, 50 healthy women, which were scheduled for abdominal gynecological surgery were randomly allocated into two groups depending of postoperative analgesic technique--morphine/ ketoprofen or lidol/ketoprofen. The quality of postoperative analgesia, total opioid consumption for the first postoperative day and unwished side effects were assessed.

[Diprivan versus midazolam in combined anaesthesia with ketamin for minor gynecological surgery].

We tested the hypothesis that diprivan/ketamine (D/K) anesthesia would offer advantages compared to midazolam/ketamine (M/K) in patients undergoing minor gynecological surgery. After patient written consent, 60 healthy women, which were scheduled for elective termination of pregnancy were randomly allocated into two groups. Operating conditions, recovery, pain, postoperative nausea and vomiting (PONV) and patient's satisfaction to anesthesia were assessed.

[Immunological aspects of postoperative analgesia after abdominal hysterectomy].

Background: Prostaglandins modulate cytokine release though increases in cAMP, regulating interleukin-6 and interleukin-10. Ketoprofen inhibits cyclo-oxygenase activity and hence prostaglandin production.

Aim: We hypothesized that ketoprofen would affect release of IL-6 and IL-10 and modulate the immune response.

[Usage of the new parenteral selective cox-2 inhibitor dynastat in the gynecologic practice].

A follow-up of 180 women was carried out. The patients having endured different gynecological operations (laparoscopy, laparohysterectomy, etc.) were divided into two main groups: half of them were treated with Dynastat (new selective COX-2 inhibitor) and the others were treated with Profenid (conventional nonsteroidal anti-inflammatory drug).

[Modern aspects of perioperative analgesia by using nonsteroidal anti-inflammatory drugs in gynecology (Part I)].

It is an actual problem how to treat acute postoperative pain by using nonsteroidal anti-inflammatory drugs. Modern concepts for perioperative administration of these drugs are very important for the usual practice. The possibilities for optimal application of nonselective or selective COX-2 inhibitors are examined in this review.

[Modern aspects of perioperative analgesia by using nonsteroidal anti-inflammatory drugs in gynecology (Part II)].

It is an actual problem how to treat acute postoperative pain by using nonsteroidal anti-inflammatory drugs. Modern concepts for perioperative administration of these drugs are very important for the usual practice. The possibilities for optimal application of nonselective or selective COX-2 inhibitors are examined in this review.

[Administration of Perfalgan (paracetamol) for postoperative analgesia in obstetrics and gynaecology].

The aim of our study is to determine the quality of postoperative analgesia by using of Perfalgan (injectable paracetamol)--alone or in combination with other analgesics for different operations in obstetric and gynecology. We have evaluated 60 women, divided into four groups each one of 15 according to the kind of surgical intervention: section cesarean, laparoscopy, laparohysterectomy or cystectomy. The effect of administered Perfalgan over postoperative pain was estimated by different objective and subjective parameters after standard general anesthesia.

[Use of low molecular weight heparin (Clexane) together with selective COX-2 inhibitor (Dynastat--once or twice per day)].

A follow-up of forty women was carried out. The patients having endured a gynecological operation (laparohysterectomy) were divided into two groups: group A--treated with Dynastat (40 mg/24h) and group B--treated with Dynastat (80mg/24h) which was combined in both groups with Clexane. The hematological and hemostatic parameters were evaluated during the early postoperative period--the first 24 hours.

[Enteral versus parenteral administration of a single dose of profenid after gynecological laparoscopy].

The aim of our study is to compare analgesic effect of single dose Profenid (Sanofi-Aventis)--100 mg administered per rectum or intravenously in woman endured gynecological laparoscopy (LS). We have evaluated 40 woman (divided into two groups each one of 20) sustained planned laparoscopy in department of gynaecology. The effect of administered Profenid over the postoperative pain has been estimated after standard general anaesthesia due to different objective and subjective parameters.

[Progress in methods of therapeutical abortions during the second trimester in gynecological clinic "Umbal - Pleven"].

The aim of the authors is to discover the progress in the methodology for the interruption of pregnancy by medical indications during the second trimester in Gynecological clinic in UMBAL - Pleven. A retrospective study has been performed for the used methods in the last 10 years. For the same period were performed abortions in 49 women by medical indications.

[Antibiotic prophylaxis on treatment outcome after gynecologic surgery].

The aim of our study is to estimate advantages and disadvantages of some antibacterial drugs which were used for prevention from infections in the early postoperative period. Our study is retrospective and involved all women which were undergoing different operations in department of gynaecology for the period January 2000 until June 2004. Due to a large number of patients and long period of time which were evaluated our study shows assume data for efficacy of different antibacterial drugs and drug combination when we using them for prevention.

[Profenid or veral for the postoperative analgesia in gynaecology].

We present our results for study and assessment of efficacy in accordance with postoperative analgesia with single dose Profenid (ketoprofen) or Veral (diclofenac) administrated per rectum. We studied 60 patients divided in two groups--group 1 (analgesia with Profenid) and group 2 (analgesia with Veral). All patients received standard endotracheal anesthesia for elective gynaecologic operations.

[Ketamine at low doses + etomidate or diazepam--a comparative clinical study of anesthesia in urology].

Eighty urological patients, divided in two equal groups, are anesthesized using two anaesthetic combinations: small dose kaliposol + etomidate, or diazepam. The obtained results point to a stability of the arterial pressure and pulse rate and prompt recovery, rendering the kalipsol-etomidate combination an alternative to the kalipsol-diazepam one which is well affirmed in urological practice.

[The clinical and anesthesiological aspects of ambulatory pediatric urological operations].

Over a five-year period, a total of 838 children, aged 0.5 to 15 years, undergo surgical treatment in the urological clinic, accounting for 16.49 per cent of all operations performed.

[Ketamine analgesia with low (subanesthetic) doses during endoscopic urological operations].

The aim of the study is analgesia of patients in urologic practice with unusual (subanesthetic) ketamine doses from 0.5 to 1 mg/kg body mass. It was applied in 50 men 50 to 70 years of age for the period 1986-1988--in 40 for transurethral resection (TUR) and in 10 for urethrotomy.