Publications by authors named "Tabita Denisia Ghete"
Article Synopsis
- The study investigates how a specific bacterium, commonly found in the stomach, interacts with different oral epithelial cell lines to understand its pathogenic potential, focusing on the role of a protein called CagA and a secretion system.
- Three oral epithelial cell lines were tested, but none showed the expected elongation response to CagA injection, indicating a resistance linked to a lack of CEACAM receptors on their surface.
- By genetically introducing CEACAM receptors into these cell lines, the researchers were able to overcome the resistance, allowing for CagA delivery and phosphorylation, while also triggering significant pro-inflammatory responses independently of CEACAM.
