A number of bacterial species control the function of the flagellar motor in response to the levels of the secondary messenger c-di-GMP, which is often mediated by c-di-GMP-binding proteins that act as molecular brakes or clutches to slow the motor rotation. The gammaproteobacterium possesses two distinct flagellar systems, the primary single polar flagellum and a secondary system with one to five lateral flagellar filaments. Here, we identified a protein, MotL, which specifically regulates the activity of the lateral, but not the polar, flagellar motors in response to the c-di-GMP levels.
View Article and Find Full Text PDFSpecies of the genus are widespread in nature in various habitats, however, little is known about phages affecting sp. Here, we report the isolation of phages from diverse freshwater environments that infect and lyse strains of and other sp. Sequence analysis and microscopic imaging strongly indicate that these phages form a so far unclassified genus, now named phage Thanatos, which can be positioned within the subfamily of (; ; ; ; ; ; ).
View Article and Find Full Text PDFBacteria commonly exhibit a high degree of cellular organization and polarity which affect many vital processes such as replication, cell division, and motility. In and other bacteria, HubP is a polar marker protein which is involved in proper chromosome segregation, placement of the chemotaxis system, and various aspects of pilus- and flagellum-mediated motility. Here, we show that HubP also recruits a transmembrane multidomain protein, PdeB, to the flagellated cell pole.
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