The impact of non-caloric artificial sweetener aspartame on female reproductive system in mice model.

Background: Artificial sweeteners, used as sugar substitutes have found their ways into almost all the food items due to the notion that they are non-caloric. Aspartame is used in numerous food products throughout the world. The primary users of aspartame include diabetics and calorie conscious people who intend to limit their calorie intake.

Physiological Impact of the Non-Nutritive Artificial Sweetener, Aspartame, and the Therapeutic Potential of Aqueous Extract of .

The present study investigated the impact of aspartame (ASP) on biochemical and histological profiles and the therapeutic potential of aqueous extract of (PN) in female Swiss albino mice (20 ± 2 g b. w.).

Environmental Impact of the Presence, Distribution, and Use of Artificial Sweeteners as Emerging Sources of Pollution.

Artificial sweeteners are posing a new threat to the environment. The water ecosystem is the primary recipient of these emerging contaminants. Once ingested, sufficient amount of these artificial sweeteners escape unchanged from the human body and are added to the environment.

The Perspective of Coronavirus Disease Outbreak: Epidemiology, Transmission, and Possible Treatment.

The outbreak of coronavirus disease 2019 (COVID-19) which emerged in Wuhan city of China has now spread to 214 countries and territories around the world and two international conveyances (the Diamond Princess cruise ship harbored in Yokohama, Japan and the Holland America's MS Zaandam cruise ship) as of October 11, 2020. The disease has been named as a coronavirus disease (COVID-19) and the virus causing the disease is known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There are currently about 36,754,395 confirmed COVID-19-infected cases and 1,064,838 confirmed deaths as of October 11, 2020.

Potential biomarkers of emotional stress induced neurodegeneration.

Mental health is a matter of great significance and interest both socially and scientifically. The present review aims to provide an informative platform about the classical biomarkers available to identify and diagnose the neurodegeneration induced by emotional stress and depression. Present article provides an expert comprehensive overview of the universally accepted markers and their mechanism of action involved in emotional stress assessment and its management.

An Overview of Ovarian Cancer: Molecular Processes Involved and Development of Target-based Chemotherapeutics.

Ovarian cancer is one of the leading gynecologic diseases with a high mortality rate worldwide. Current statistical studies on cancer reveal that over the past two decades, the fifth most common cause of death related to cancer in females of the western world is ovarian cancer. In spite of significant strides made in genomics, proteomics and radiomics, there has been little progress in transitioning these research advances into effective clinical administration of ovarian cancer.

Health Implications Associated with Aspartame Consumption: A Substantial Review.

Aspartame, an artificial sweetening agent belongs to dipeptide chemical category with a very strong sweetening potential. Although research findings in humans and non-human primates have demonstrated numerous negative effects of aspartame (biochemical, histological, neurological, behavioral, genetic etc)., the status of aspartame is still debatable.

Effect of cold stress on infanticide by female Swiss albino mice : a pilot study.

Background: Mice are widely accepted research models of great clinical significance. Maintenance of laboratory mice breed is an essential aspect for performing research activities in various fields of science. Infanticide is one of the prominent causes of litter loss during maintenance of laboratory mice stock.

Estimation of Anti-HIV Activity of HEPT Analogues Using MLR, ANN, and SVM Techniques.

The present study deals with the estimation of the anti-HIV activity (log1/C) of a large set of 107 HEPT analogues using molecular descriptors which are responsible for the anti-HIV activity. The study has been undertaken by three techniques MLR, ANN, and SVM. The MLR model fits the train set with R (2)=0.