Publications by authors named "Tabassum Binte Kashem"
Article Synopsis
- A drug called 1,4-DPCA acts as a PHD inhibitor, promoting tissue regeneration by boosting the activity of Hif-1α even when oxygen levels are normal.
- Researchers designed a drug delivery system using polydopamine (PDA) to encapsulate 1,4-DPCA, which helps enhance its regenerative effects by producing reactive oxygen species (ROS) that improve cellular defenses.
- The study found that this combined approach resulted in about six times more bone regeneration in mice compared to untreated controls.
Subcutaneous (SC) administration of chemotherapeutics combined with near-infrared (NIR) light activation can effectively target skin tumors by triggering localized drug release and enhancing cytotoxic effects. In this study, we developed NIR-responsive indocyanine green (ICG) and the chemotherapeutic agent doxorubicin (Dox) loaded into gelatin nanoparticles (NPs) for SC delivery in a skin tumor-bearing mouse model. Histological examination (hematoxylin and eosin staining) confirmed the successful delivery and swelling behavior of the Dox/ICG-loaded gelatin NPs at the SC site.
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