Encapsulation of walnut husk and pomegranate peel extracts by alginate and chitosan-coated nanoemulsions.

Walnut husk extract (WHE) and pomegranate peel extract (PPE) were produced through ultrasound-assisted extraction. Total phenol, flavonoid and tannin contents (TPC, TFC and TTC), antioxidant and antimicrobial activities were determined. The best extracts were used for production of alginate (Alg) and chitosan (CS)-coated nanoemulsions containing WHE (NWHE) or PPE (NPPE).

Adherence to the dietary approaches to stop hypertension (DASH) and risk of pancreatic steatosis.

Background: The Dietary Approach to Stop Hypertension (DASH) has shown positive effects on various health factors that may be related to pancreatic steatosis (PS). This study aimed to investigate the association between adherence to the DASH diet and the risk of developing PS.

Methods: This case-control study was conducted on 278 patients diagnosed with gallstone disease and referred to Taleghani Hospital (Tehran, Iran).

Clinical outcome of surgically treated displaced acetabular fractures with central dislocation using combined anterior and medial plating.

Aim: Acetabular fractures are complex articular fractures with a big challenge for orthopaedic surgeons. Surgically managed displaced fractures carry favourable outcomes, especially if the articular surface is reduced accurately. This study aims to assess the clinical outcomes of surgically fixed displaced acetabular fractures with central dislocation using combined anterior and medial plating.

The association between plant-based diet indices and risk of mortality in patients with cirrhosis: a cohort study.

Background: Following a plant-based diet is associated with a wide range of health benefits. The current study aimed to investigate the association between plant-based diet indices, specifically the plant-based diet index (PDI), healthful PDI (hPDI), and unhealthful PDI (uPDI) and risk of mortality in cirrhotic patients.

Methods: This cohort study included a total of 121 patients with cirrhosis, who were followed for four years.

Methodological approaches in developing and implementing digital health interventions amongst underserved women.

Background: Minority populations are utilizing mobile health applications more frequently to access health information. One group that may benefit from using mHealth technology is underserved women, specifically those on community supervision.

Objective: Discuss methodological approaches for navigating digital health strategies to address underserved women's health disparities.

STING pathway as a cancer immunotherapy: Progress and challenges in activating anti-tumor immunity.

The stimulator of the interferon genes (STING) signaling pathway plays a crucial role in innate immunity by detecting cytoplasmic DNA and initiating antiviral host defense mechanisms. The STING cascade is triggered when the enzyme cyclic GMP-AMP synthase (cGAS) binds cytosolic DNA and synthesizes the secondary messenger cGAMP. cGAMP activates the endoplasmic reticulum adaptor STING, leading to the activation of kinases TBK1 and IRF3 that induce interferon production.

An unusual case of retroperitoneal synovial sarcoma with CT, MRI, and F-18 FDG PET/CT findings.

Synovial sarcoma, predominantly found in the extremities, rarely occurs in the retroperitoneum. Tumors can often grow to a considerable size before diagnosis, which warrant the critical importance of early detection to minimize morbidity and mortality. While the final diagnosis relies on pathologic examination, imaging plays a crucial role in early detection.

Is There a Role for Ordering a DEXA (Dual Energy X-Ray Absorptiometry) Scan for Patients with Symptomatic Advanced Knee Osteoarthritis?

Background: Osteoarthritis of the knee (OA) and osteoporosis are two conditions that have a significant impact on society, have a great impact on quality of life, and can lead to functional impairment. However, the relationship between knee OA and osteoporosis is unclear.

Objective: The aim of this study was to examine if there is a link between symptomatic advanced knee osteoarthritis and low bone mineral density.

Chronic diarrhea secondary to canine leishmaniosis: Case series.

Chronic diarrhea is a clinical sign associated with canine leishmaniosis, varying from 3 % to 30 % of prevalence. However, its occurrence in dogs has been mostly associated with chronic kidney or liver disease. Leishmania organisms can cause inflammation of the digestive tract with chronic diarrhea as the only clinical manifestation, although it has been poorly documented in dogs.

Outcomes of Treating Tibial Shaft Fractures Using Intramedullary Nailing (IMN) versus Minimally Invasive Percutaneous Plate Osteosynthesis (MIPPO).

Background: Tibia shaft fractures are one of the most common long-bone fractures, second most common open sport-related injuries and they are estimated to occur in 4 percent of the senior population.

Objective: Management of tibial fractures has been updating to achieve the best outcomes and avoid complications especially when talking about most common long bone fractures. Less invasive fixation techniques are the preferred ones to reduce surrounding soft tissue injury, improve healing process and decrease complications.

The Fusion of and Arises from a -Splicing Event in Normal and Transformed Human Cells.

Chimeric RNAs are often associated with chromosomal rearrangements in cancer. In addition, they are also widely detected in normal tissues, contributing to transcriptomic complexity. Despite their prevalence, little is known about the characteristics and functions of chimeric RNAs.

A template-free approach for waveform extraction of gravitational wave events.

We develop a general data-driven and template-free method for the extraction of event waveforms in the presence of background noise. Recent gravitational-wave observations provide one of the significant scientific areas requiring data analysis and waveform extraction capability. We use our method to find the waveforms for the reported events from the first, second, and third LIGO observation runs (O1, O2, and O3).

Correction: Dynamical time scales of friction dynamics in active microrheology of a model glass.

Correction for 'Dynamical time scales of friction dynamics in active microrheology of a model glass' by A. Madanchi et al., Soft Matter, 2021, DOI: 10.

Clinical findings, neurological manifestations and survival of dogs with insulinoma: 116 cases (2009-2020).

Objectives: To review the clinical findings and outcome in dogs diagnosed with insulinoma, and to assess which factors are predictors of overall survival. Additionally, to describe the neurological manifestations of this population and their correlation with survival.

Materials And Methods: Retrospective multicentric study of canine insulinoma cases (2009 to 2020).

An improved production and purification protocol for recombinant soluble human fibroblast activation protein alpha.

Fibroblast activation protein alpha (FAP) is a cell-surface expressed type II glycoprotein that has a unique proteolytic activity. FAP has active soluble forms that retain the extracellular portion but lack the transmembrane domain and cytoplasmic tail. FAP expression is normally very low in adult tissue but is highly expressed by activated fibroblasts in sites of tissue remodelling.

Heterologous expression, purification, and refolding of SRY protein: role of L-arginine as analyzed by simulation and practical study.

Escherichia coli is a widely-used cell factory for recombinant protein production, nevertheless, high amount of produced protein is seen in aggregated form. The purpose of this study was to improve the solubility of recombinant bovine sex-determining region Y protein (rbSRY) by exploring the effect of temperature, inducer, and water-arginine mixed solvent. Codon-optimized rbSRY expressed in Rosetta-gami B (DE3) pLysS and purified by NI-NTA His-select affinity chromatography in the native and denaturing conditions.

Effects of Vitamin D on Apoptosis and Quality of Sperm in Asthenozoospermia.

Objective: Vitamin D receptor (VDR) is expressed in human spermatozoa. However, the role of vitamin D (VD) in human male reproduction has not yet been clarified. In this study, effects of VD on sperm parameters and its apoptosis in asthenozoospermic and healthy men were evaluated.

Feline leishmaniosis: diagnosis, treatment and outcome in 16 cats.

Objectives: Leishmaniosis is a vector-borne disease and in European countries is caused by . Cats are considered secondary reservoirs of the infection in endemic areas. The objective of this retrospective study is to describe the clinical findings, diagnosis, treatment and outcome of feline leishmaniosis (FeL) in 16 cats in Spain.

Analysis and data-driven reconstruction of bivariate jump-diffusion processes.

We introduce the bivariate jump-diffusion process, consisting of two-dimensional diffusion and two-dimensional jumps, that can be coupled to one another. We present a data-driven, nonparametric estimation procedure of higher-order (up to 8) Kramers-Moyal coefficients that allows one to reconstruct relevant aspects of the underlying jump-diffusion processes and to recover the underlying parameters. The procedure is validated with numerically integrated data using synthetic bivariate time series from continuous and discontinuous processes.

A topology-dynamics-based control strategy for multi-dimensional complex networked dynamical systems.

Complex systems are omnipresent and play a vital role in in our every-day lives. Adverse behavior of such systems has generated considerable interest in being able to control complex systems modeled as networks. Here, we propose a topology-dynamics-based approach for controlling complex systems modeled as networks of coupled multi-dimensional dynamical entities.

Exact enumeration approach to first-passage time distribution of non-Markov random walks.

We propose an analytical approach to study non-Markov random walks by employing an exact enumeration method. Using the method, we derive an exact expansion for the first-passage time (FPT) distribution of any continuous differentiable non-Markov random walk with Gaussian or non-Gaussian multivariate distribution. As an example, we study the FPT distribution of the fractional Brownian motion with a Hurst exponent H∈(1/2,1) that describes numerous non-Markov stochastic phenomena in physics, biology, and geology and for which the limit H=1/2 represents a Markov process.