Publications by authors named "TaLesa Aderohunmu"
J Clin Microbiol
August 2022
Article Synopsis
- The CDC uses a two-test algorithm, plus a tiebreaker, to diagnose chronic Chagas disease caused by Trypanosoma cruzi due to the lack of a gold-standard test.
- The Ortho T. cruzi ELISA Test System was evaluated against this CDC algorithm, showing a 90% concordance rate overall and 92% when excluding certain cross-reactive specimens.
- The Ortho Test also demonstrated minimal cross-reactivity with other parasitic infections and is expected to enhance the diagnosis of chronic Chagas disease as it is FDA-cleared for clinical use.
J Clin Microbiol
October 2021
Article Synopsis
- The study focuses on a method to improve the detection of antibodies for babesiosis caused by a specific agent in the western U.S.
- Researchers utilized a proteomics technique to identify proteins that could enhance serological testing, moving away from the need for infected hamsters' blood cells.
- Two recombinant proteins, AAY83295.1 and AAY83296.1, showed promising results in a multiplex bead assay, with AAY83295.1 having 100% sensitivity and AAY83296.1 showing 96% specificity, making this approach potentially beneficial for diagnosis and blood screening.
