Treatment of hay fever with alum precipitated pyridine (Allpyral) ragweed pollen extracts--a clinical reappraisal.

This report reviews the results of prophylactic immunotherapy carried out on 105 ragweed hay fever patients treated for at least two years with an alum-precipitated pyridine ragweed (Allpyral) extracts prepared from equal parts of low and giant ragweed pollen. Good or excellent clinical results were obtained in most patients with a minimum of reaction, notably constitutional ones, even when the interval between injections was quite prolonged. Seasonal asthma rarely occurred in the treated patients.

"Steroid-phobia" in asthma management.

Excellent clinical results were obtained in 85 patients with chronic asthma who took corticosteroids (mostly triamcinolone) on a long-term basis for periods varying from one to 26 years. There was a minimum of side-effects, none serious; the most discomforting were ecchymosis and a tendency to easy bruising. The results of this and previous studies have convinced the author that corticosteroids, if judiciously used, are the most valuable adjunct we have in the treatment of acute and chronic asthma.

Prolonged immunotherapy with alum-precipitated pyridine ragweed extracts-a clinical and immunological study.

In 18 ragweed hay fever patients who received injections of alum-precipitated pyridine (Allpyral) ragweed extracts in maintenance doses of between 6000 and 8000 P.N.U.

Hyposensitization therapy with alum-precipitated pyridine extracts in animal dander sensitive patients.

Hyposensitization therapy with APP extracts was found to be effective in 80% of 185 patients allergic to animals (96 to cats, 84 to dogs and 5 to horses) with a minimum of reactions (2.5 local and 0.2% constitutional).

Contact urticaria from cephalosporins.

A rare instance of contact-type urticaria resulting from an acquired sensitization to cephalosporin compounds in a chemist is reported. Patch tests elicited an immediate urticarial rather than a delayed contact-type response. Similar control tests to other antibiotics gave negative results.