The impact of the board of directors and the audit committee on the transparency of financial information of companies listed in a frontier market.

This study aims to evaluate the impact of factors representing the Board of Directors (BOD) and Audit Committee (AC) on financial information transparency (FIT) in a frontier market. FIT is measured through three indicators that reflect financial non-transparency: earnings aggressiveness (EA), earnings smoothing (ES) and loss avoidance (LA). Research data was collected from 338 companies listed on the Vietnam Stock Exchange (HOSE and HNX) from 2012 to 2022.

Discovery of Vascular Endothelial Growth Factor Receptor 2 Inhibitors Employing Junction Tree Variational Autoencoder with Bayesian Optimization and Gradient Ascent.

In the development of anticancer medications, vascular endothelial growth factor receptor 2 (VEGFR-2), which belongs to the protein tyrosine kinase family, emerges as one of the most significant targets of interest. The ongoing Food and Drug Administration (FDA) approval of novel therapeutic medicines toward VEGFR-2 emphasizes the urgent need to discover sophisticated molecular structures that are capable of reliably limiting VEGFR-2 activity. Recognizing the huge potential of deep-learning-based molecular model advancements, we focused our study on exploring the chemical space to find small molecules potentially inhibiting VEGFR-2.

Description and pathology of a new genus and species of fish blood fluke (Digenea: Aporocotylidae Odhner, 1912) infecting white mullet, Valenciennes, 1836 (Mugiliformes: Mugilidae) in Mobile Bay (northern Gulf of Mexico) with a phylogenetic analysis.

Three fish blood flukes (Aporocotylidae Odhner, 1912) infect mullets (Mugiliformes: Mugilidae): Yamaguti, 1970 and Martin, 1975 infect striped mullet, Linnaeus, 1758 in the Central Pacific Ocean (Hawaiian Islands) and Brisbane River (Australia), respectively; Knoff & Amato, 1992 infects Lebranche mullet, Valenciennes, 1836 from the Southwestern Atlantic Ocean (Brazil). White mullets were cast-netted from the mouth of Deer River, a coastal saltmarsh of Mobile Bay, in the north-central Gulf of Mexico and examined for blood fluke infections. Specimens of Warren & Bullard n.

Innovative virtual screening of PD-L1 inhibitors: the synergy of molecular similarity, neural networks and GNINA docking.

Immune checkpoint inhibitors targeting PD-L1 are crucial in cancer research for preventing cancer cells from evading the immune system. This study developed a screening model combining ANN, molecular similarity, and GNINA 1.0 docking to target PD-L1.

Computational Design of 3D Lantern Organic Framework.

This study employed a computational approach, particularly Density Functional Theory at B3LYP-D3/6-31+G(d) level to design two new classes of three-dimensional (3D) Lantern Organic Frameworks (LOFs) materials based on trisilasumanene and porphyrin core building units. Particularly, we detail strategies for transitioning from 1D-LOF nanowires to extended 3D structures: first by connecting planar-molecule base units of trisilasumanene or porphyrin using benzene-based linkers, and then connecting silicon anchoring atoms on the bases with other bases that are vertically stacked by sp-hydrocarbon chains. The 3D-LOF structures are designed to have different pore sizes through the use of various bases, bridges, and linkers.

Correlation of resin composite translucency and IOS accuracy: An study.

Background: Different restoration materials have different optical characteristics that influence the intraoral scanner's (IOS) image accuracy. The purpose of this investigation was to investigate how composite translucency affected the accuracy of IOS.

Material And Methods: GC G-aenial Universal Injectable JE composite plates were used for the study at 3 thicknesses (1-2-3mm).

First Azygiid Reported from Africa or a Characiform Fish: Plenivitellinum kifi n. gen., n. sp. (Digenea: Azygiidae) Infecting the Gut of African Tigerfish, Hydrocynus vittatus Castelnau, 1861 (Characiformes: Alestidae) from the Kavango River.

Purpose: This paper aims to describe Plenivitellinum kifi n. gen., n.

Nature of partial sigma bond.

This study investigates the formation of partial sigma (σ) covalent bonds in experimentally synthesizable biradicals formed from hydrogenated and fluorinated C, C, and C cage structures, by assessing their stability, geometry, and bonding character in singlet and triplet states using restricted B3LYP-D3/6-31+G(d,p) theory, natural bond orbital (NBO) analysis, and complete active space self-consistent field (CASSCF) method. The results show that these partial σ bonds have Wiberg bond orders of 0.38 to 0.

Novel machine learning approach toward classification model of HIV-1 integrase inhibitors.

HIV-1 (human immunodeficiency virus-1) has been causing severe pandemics by attacking the immune system of its host. Left untreated, it can lead to AIDS (acquired immunodeficiency syndrome), where death is inevitable due to opportunistic diseases. Therefore, discovering new antiviral drugs against HIV-1 is crucial.

Integration of the Butina algorithm and ensemble learning strategies for the advancement of a pharmacophore ligand-based model: an investigation of apelin agonists.

3D pharmacophore models describe the ligand's chemical interactions in their bioactive conformation. They offer a simple but sophisticated approach to decipher the chemically encoded ligand information, making them a valuable tool in drug design. Our research summarized the key studies for applying 3D pharmacophore models in virtual screening for 6,944 compounds of APJ receptor agonists.

DULCITRANSVERSOTREMA N. GEN. (DIGENEA: TRANSVERSOTREMATIDAE) AND FIRST MORPHOLOGICAL AND NUCLEOTIDE-BASED CONFIRMATION OF THE LIFE CYCLE OF A TRANSVERSOTREMATID IN NORTH AMERICA.

We propose Dulcitransversotrema n. gen. for the freshwater transversotrematids Dulcitransversotrema patialense (Soparkar, 1924) n.

Acceptance and User Experiences of a Wearable Device for the Management of Hospitalized Patients in COVID-19-Designated Wards in Ho Chi Minh City, Vietnam: Action Learning Project.

Background: Wearable devices have been used extensively both inside and outside of the hospital setting. During the COVID-19 pandemic, in some contexts, there was an increased need to remotely monitor pulse and saturated oxygen for patients due to the lack of staff and bedside monitors.

Objective: A prototype of a remote monitoring system using wearable pulse oximeter devices was implemented at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam, from August to December 2021.

A Combination of Blue Light at 460 nm and HO for the Safe and Effective Eradication of in an Infected Mouse Skin Abrasion Model.

Antibiotic-free approaches are more important than ever to address the rapidly growing problem of the antibiotic resistance crisis. The photolysis of the bacterial virulence factor staphyloxanthin using blue light at 460 nm (BL460 nm) has been found to effectively attenuate to chemical and physical agents. However, phototherapy using BL640 nm still needs to be investigated in detail for its safety in eradicating in vitro and in vivo.

Description, life cycle, and phylogenetics of Proterometra wigglewomble n. sp. (Digenea: Azygiidae) from the Cahaba River, Alabama, U.S.A.

We herein describe Proterometra wigglewomble n. sp. (Digenea: Azygiidae: Azygiinae) from the Cahaba River, Alabama, USA, which asexually reproduces in the compact elimia, Elimia showalteri (Lea, 1860) (Cerithioidea: Pleuroceridae) and matures in the oesophagus of the blackbanded darter, Percina nigrofasciata (Agassiz, 1854) (Perciformes: Percidae).

Phytochemistry and Cytotoxic Activity of Pericarp on MDA-MB-468 Cell Lines.

The extracts of pericarp were investigated on the MDA-MB-468, a breast cancer cell line, at desired concentration (1-50 μg/mL). The results showed that the dichloromethane (DCM) extract exhibited the strongest toxicity and was carried out subsequently. A total of nine compounds were isolated from the DCM extract using column chromatography and recrystallization, of which their structures were determined.

Effects of Lianhuaqingwen Capsules in adults with mild-to-moderate coronavirus disease 2019: an international, multicenter, double-blind, randomized controlled trial.

Background: In a randomized trial, Lianhuaqingwen (LHQW) capsule was effective for accelerating symptom recovery among patients with coronavirus disease 2019 (COVID-19). However, the lack of blinding and limited sample sizes decreased the level of clinical evidence.

Objectives: To evaluate the efficacy and safety of LHQW capsule in adults with mild-to-moderate COVID-19.

A model-free terminal sliding mode control for robots: Achieving fixed-time prescribed performance and convergence.

This paper introduces a new control strategy for robot manipulators, specifically designed to tackle the challenges associated with traditional model-based sliding mode (SM) controller design. These challenges include the need for accurately computed system models, knowledge of disturbance upper bounds, fixed-time convergence, prescribed performance, and the generation of chattering. To overcome these obstacles, we propose the incorporation of a neural network (NN) that effectively addresses these issues by removing the constraint of a precise system model.

Atom-Based Machine Learning Model for Quantitative Property-Structure Relationship of Electronic Properties of Fusenes and Substituted Fusenes.

This study presents the development of machine-learning-based quantitative structure-property relationship (QSPR) models for predicting electron affinity, ionization potential, and band gap of fusenes from different chemical classes. Three variants of the atom-based Weisfeiler-Lehman (WL) graph kernel method and the machine learning model Gaussian process regressor (GPR) were used. The data pool comprises polycyclic aromatic hydrocarbons (PAHs), thienoacenes, cyano-substituted PAHs, and nitro-substituted PAHs computed with density functional theory (DFT) at the B3LYP-D3/6-31+G(d) level of theory.

Optimal Coatings of CoO Anodes for Acidic Water Electrooxidation.

Implementation of proton-exchange membrane water electrolyzers for large-scale sustainable hydrogen production requires the replacement of scarce noble-metal anode electrocatalysts with low-cost alternatives. However, such earth-abundant materials often exhibit inadequate stability and/or catalytic activity at low pH, especially at high rates of the anodic oxygen evolution reaction (OER). Here, the authors explore the influence of a dielectric nanoscale-thin oxide layer, namely AlO, SiO, TiO, SnO, and HfO, prepared by atomic layer deposition, on the stability and catalytic activity of low-cost and active but insufficiently stable CoO anodes.

Exploration of 1,2,3-triazolo fused triterpenoids as inhibitors of human coronavirus 229E targeting the viral nsp15 protein.

The coronavirus disease-19 (COVID-19) pandemic has raised major interest in innovative drug concepts to suppress human coronavirus (HCoV) infections. We previously reported on a class of 1,2,3-triazolo fused betulonic acid derivatives causing strong inhibition of HCoV-229E replication via the viral nsp15 protein, which is proposedly related to compound binding at an intermonomer interface in hexameric nsp15. In the present study, we further explored the structure-activity relationship (SAR), by varying the substituent at the 1,2,3-triazolo ring as well as the triterpenoid skeleton.

High accurate and explainable multi-pill detection framework with graph neural network-assisted multimodal data fusion.

Due to the significant resemblance in visual appearance, pill misuse is prevalent and has become a critical issue, responsible for one-third of all deaths worldwide. Pill identification, thus, is a crucial concern that needs to be investigated thoroughly. Recently, several attempts have been made to exploit deep learning to tackle the pill identification problem.

A new species of Ellipsomyxa Køie, 2003 (Bivalvulida) infecting the gall bladder of Pangasius macronema Bleeker (Siluriformes: Pangasiidae) from the Mekong River Delta, Vietnam.

During a parasitological survey of freshwater fishes in the Mekong River Delta, Vietnam, disporic plasmodia containing myxospores morphologically consistent with Ellipsomyxa Køie, 2003 (Bivalvulida) were observed infecting the gall bladder of Pangasius macronema Bleeker (Siluriformes: Pangasiidae). Herein, we use morphology and small subunit ribosomal DNA (SSU rDNA, 18S) sequence data to describe Ellipsomyxa intravesica Ksepka & Bullard n. sp.

Surveillance and treatment of primary hepatocellular carcinoma (aka. STOP HCC): protocol for a prospective cohort study of high-risk patients for HCC using GALAD-score.

Background: Vietnam and Saudi Arabia have high disease burden of primary hepatocellular carcinoma (HCC). Early detection in asymptomatic patients at risk for HCC is a strategy to improve survival outcomes in HCC management. GALAD score, a serum-based panel, has demonstrated promising clinical utility in HCC management.

Understanding Structure-Activity Relationship in Pt-loaded g-C N for Efficient Solar- Photoreforming of Polyethylene Terephthalate Plastic and Hydrogen Production.

Coupling the hydrogen evolution reaction with plastic waste photoreforming provides a synergistic path for simultaneous production of green hydrogen and recycling of post-consumer products, two major enablers for establishment of a circular economy. Graphitic carbon nitride (g-C N ) is a promising photocatalyst due to its suitable optoelectronic and physicochemical properties, and inexpensive fabrication. Herein, a mechanistic investigation of the structure-activity relationship of g-C N for poly(ethylene terephthalate) (PET) photoreforming is reported by carefully controlling its fabrication from a subset of earth-abundant precursors, such as dicyandiamide, melamine, urea, and thiourea.