Publications by authors named "TAWIL G"

Replacement of missing posterior mandibular teeth in severely atrophied jaws can be quite challenging. Various treatment options have been proposed for the rehabilitation of the deficient posterior mandible with implant-supported prostheses. Depending on the clinical situation, it may be feasible to place implants lateral to the inferior alveolar nerve, which represents a viable treatment option under the proper circumstances.

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Titanium remains the material of choice in the manufacturing of dental implants because of its exceptional biologic and mechanical properties. However, cases of allergy to titanium have been reported in the literature causing skin, mucosal reactions, systemic symptoms, and eventually implant exfoliation. Although the frequency of these cases varied between 0.

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Chronic periodontitis progression may go through phases of remission and exacerbation. The possibility of periodontal pathogens translocating from infected periodontal sites to peri-implant sites has been reported. Additionally, a history of periodontal disease seems to be a risk factor for peri-implantitis.

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Purpose: Sinus floor elevation using the lateral approach and bone window repositioning and a xenogeneic bone substitute (Cerabone) has been well documented clinically. The purpose of this histologic and histomorphometric study was to determine the fate of the window, its contributing role in the healing process, and the osseoconductivity and resorption potential of the high-temperature sintered bovine bone used, as well as to correlate the histomorphometric results with sinus depth and lateral wall thickness as determined on cone beam computed tomography (CBCT).

Materials And Methods: Thirty biopsy specimens were harvested from the lateral side of the maxilla of patients operated on for sinus floor elevation and implant placement at two postoperative periods: early, group 1 (mean: 5.

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Purpose: To determine the potential complications and clinical outcomes using the lateral sinus elevation technique with window repositioning.

Materials And Methods: One hundred nine sinus elevations were performed on 102 consecutively treated patients. Following lateral window outward fracturing, sinus mucosa was elevated, and the sinus was grafted with anorganic bovine bone.

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Today, development of slowly digestible food with positive health impact and production of biofuels is a matter of intense research. The latter is achieved via enzymatic hydrolysis of starch or biomass such as lignocellulose. Free label imaging, using UV autofluorescence, provides a great tool to follow one single enzyme when acting on a non-UV-fluorescent substrate.

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Pro-inflammatory cytokines, i.e., IL-1 mediate the inflammatory response and are genetically regulated in periodontal diseases.

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A new α-amylase from Anoxybacillus flavothermus (AFA) was found to be effective in hydrolyzing raw starch in production of glucose syrup at temperatures below the starch gelatinization temperature. AFA is very efficient, leading to 77% hydrolysis of a 31% raw starch suspension. The final hydrolysis degree is reached in 2-3h at starch concentrations lower than 15% and 8-24h at higher concentrations.

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Synchrotron UV fluorescence microscopy was used for the first time to visualize the adsorption and diffusion of an enzyme while degrading a solid substrate. The degradation pathway of single starch granules by two amylases, optimized for biofuel production and industrial starch hydrolysis, was followed by tryptophan fluorescence (excitation at 280 nm, emission filter at 300-400 nm) and visible light imaging. Thus, both the adsorption of enzyme onto starch granules at 283 nm resolution and the resulting morphological changes were recorded at different stages of hydrolysis.

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A new α-amylase from Rhizomucor sp. (RA) was studied in detail due to its very efficient hydrolysis of raw starch granules at low temperature (32 °C). RA contains a starch binding domain (SBD) connected to the core amylase catalytic domain by a O-glycosylated linker.

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Purpose: To investigate the effect of type-2 diabetes on implant survival and complication rate.

Materials And Methods: Prospective study enrolling type-2 diabetic patients suffering from edentulism, having a mean perioperative HbA1c level of 7.2%, and compliant with a maintenance program.

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The purpose of this case report is to demonstrate the relation between occlusal overload and peri-implant bone loss and the reversal of the situation after removal of the offending forces. The placement of an unstable removable prosthesis on 3 well-integrated implants that had been stable for 9 years caused noticeable bone loss after 6 months. The elimination of the traumatic occlusion reversed the situation, and a remarkable healing of the peri-implant tissue occurred until the pretrauma condition was nearly restored.

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Purpose: Implants shorter than 10 mm can be a long-term solution for sites with limited bone height. The purpose of this study was to determine the influence of some prosthetic factors on the survival and complication rates.

Materials And Methods: Two hundred sixty-two short machined-surface Brånemark System implants were consecutively placed in 109 patients and followed for a mean of 53 months.

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Purpose: Bone resorption following tooth loss often limits the quantity of bone available for implant placement. The purpose of the present study was to evaluate the clinical outcome of 10-mm or shorter machined-surface implants when used exclusively in the treatment of various forms of edentulism.

Materials And Methods: Two hundred sixty-nine screw-type Brånemark System implants (Nobel Biocare), 10 mm or shorter, were placed in 111 consecutively treated patients.

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Purpose: The purpose of this study was to report the clinical results obtained with 5-mm diameter regular-platform Brånemark implants after 2 to 5 years of follow-up. A secondary aim was to compare the clinical outcome to that of adjacently placed standard 3.75-mm fixtures in the same patients under the same operative condition and in the same prosthetic construction.

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The aim of this study was to determine the efficacy of a bioresorbable collagen membrane (Bio-Gide) in combination with autogenous bone grafts in the treatment of peri-implant dehiscences, fenestrations, or limited vertical defects. Eighteen titanium dental implants with exposed threads placed in 17 patients were studied. Autogenous bone was used in all cases to fill the defect and maintain the space underneath the barrier.

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Xenografts have been used extensively, either alone or in combination with autogenous bone, in sinus floor elevation techniques. However, controversy exists regarding the need to cover the lateral osteotomy site with a membrane. Also, the healing period before loading remains undefined when machined-surface implants are placed.

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Three novel series of 2,6-di-tert-butyl-1,4-benzoquinone derivatives were synthesized: 4-[(3,4-disubstituted-2,3-dihydrothiazol-2-ylidene) hydrazono]-2,6-di-tert-butyl-2,5-cyclohexadien-1-ones, 4-[(3-substituted-5-carbethoxy-4-methyl-2,3-dihydrothiazol-2- ylidene)hydrazono]-2,6-di-tert-butyl-2,5-cyclohexadien-1-one s, and 4-[(3-substituted-4-oxothiazolidin-2-ylidene)hydrazono]-2,6- di-tert- butyl-2,5-cyclohexadien-1-ones. These compounds were prepared by cyclization of the new 4-(N-substituted thiocarbamoylhydrazono)-2,6-di-tert-butyl-2,5-cyclohexadien- 1-ones with phenacyl bromides, ethyl alpha-chloroacetoacetate and ethyl bromoacetate, respectively. Antimicrobial testing of the prepared compounds and of the key intermediate thiosemicarbazones was performed.

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This work reports further studies of protein transport parameters in the new technique called analytical SPLITT fractionation. The SPLITT fractionation channel mimics a dialysis-like separation utilizing differential transport across an ultra-thin lamina flowing through a channel. The flowing stream is split into two sub-streams at the channel outlet, between which the protein is distributed.

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A clinical study involving 30 patients randomly selected in the department of endodontics at the Saint Joseph University of Beirut and in private practice was carried out. The use of "Obtura", a high-heat thermoplasticized gutta-percha system seems to be satisfactory, the findings stressed the advantages and the disadvantages of the technique and the material. Some suggestions are advanced in order to make the use of the technique easier and more efficient.

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Three series of alkyloxybenzamido derivatives have been prepared. The first comprises N1-[4-(4-alkyloxybenzamido)benzoyl]-N2-substituted alkylidene hydrazine, the second involves 1-[4-(4-alkyloxybenzamido)benzoyl]-4-alkyl, aryl, or aralkyl-3-thiosemicarbazides, and the third includes 1-substituted-5-[4-(4-alkyloxybenzamido)phenyl]-1,3,4-triazole-2-t hione. Representative samples of the prepared compounds were tested for their in-vitro antimicrobial activity.

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Combination of amoxycillin (1) and dicloxacillin (2) showed synergistic bacteriostatic and bactericidal activities against 15 clinical isolates of Staphylococcus aureus, including 3 beta-lactamase-producing strains.

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In chronic P. aeruginosa infection, lung tissue damage is induced by either the microorganism or the inflammatory response. We investigated, in an animal model, whether a non-steroidal anti-inflammatory drug, ibuprofen, reduced lung inflammation produced by P.

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Three experimental groups of patients with urticaria, psoriasis and alopecia were compared for hostile personality characteristics, states of anxiety and depression, neurotic syndromes and stress with a control group of patients with other skin diseases. The patients from each experimental group were found to be less dominant, more intropunitive, more extrapunitive and more neurotic than the control group. The following neurotic syndromes differentiated the experimental groups: non-specific anxiety states in urticaria patients; neurotic depression in the patients with alopecia, and a variety of neurotic syndromes in the psoriasis patients.

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