Publications by authors named "T van der Sloten"
Objective: To investigate the association between joint manifestations of vascular ageing (VA) and hypertension.
Methods: We used baseline (2008-2012) and follow-up data (up to 2024) from the Paris Prospective Study III, a French cohort of 10,157 participants. Prevalent and incident hypertension were determined at baseline (blood pressure ≥140/90 mmHg or on medication) and at 2, 4, 6, 8 and 10 years of follow-up (self-reported antihypertensive treatment).
Article Synopsis
- This study examined the link between plasma biomarkers indicating endothelial dysfunction and cognitive performance in a sample of 9,414 older adults from the Netherlands, aged 57 to 93 years.
- Researchers created a composite score from three specific biomarkers and assessed various cognitive functions like executive function and memory.
- Results indicated a small, consistent association between higher endothelial dysfunction scores and poorer cognitive performance, but no evidence suggested that these markers influenced cognitive decline over time.
Article Synopsis
- The study investigated how age, education, and sex/gender relate to performance in semantic fluency, which is the ability to generate words within a certain category.
- Data from 2,391 individuals across three different cohorts were analyzed, measuring factors like average cluster size and lexical decision response time in addition to the total number of words generated.
- Results indicated that older age and being female were both linked to lower performance in word generation, while higher education correlated with better performance across various metrics, showing consistent trends across different cohorts.