Publications by authors named "T van de Zande"

Background: Physical capacity and physical activity are important aspects of physical functioning and quality of life in people with a chronic disease such as Parkinson disease (PD) or chronic obstructive pulmonary disease (COPD). Both physical capacity and physical activity are currently measured in the clinic using standardized questionnaires and tests, such as the 6-minute walk test (6MWT) and the Timed Up and Go test (TUG). However, relying only on in-clinic tests is suboptimal since they offer limited information on how a person functions in daily life and how functioning fluctuates throughout the day.

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Article Synopsis
  • The study highlights that historical underrepresentation of females, younger individuals with Parkinson's disease (PD), and non-white populations in clinical research needs to be addressed, while also emphasizing the importance of studying non-motor symptoms.
  • Investigators analyzed a dataset from a Dutch center, looking at trends in female participation, mean age, native Dutch representation, ethnicity reporting, and the assessment of non-motor symptoms over a 19-year period (2003-2021).
  • Findings show no significant changes in demographics over time, indicating a consistent mean age of 66 years and a 39% female representation; however, older and non-native Dutch individuals remain underrepresented, highlighting the need for more diverse research subjects in
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Background: Our understanding of the etiology, pathophysiology, phenotypic diversity, and progression of Parkinson's disease has stagnated. Consequently, patients do not receive the best care, leading to unnecessary disability, and to mounting costs for society. The Personalized Parkinson Project (PPP) proposes an unbiased approach to biomarker development with multiple biomarkers measured longitudinally.

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Electrochemical conversion of micropollutants in real gray water effluent was studied for the first time. Six compounds that are frequently found in personal care and household products, namely methylparaben, propylparaben, bisphenol A, triclosan, galaxolide, and 4- methylbenzilidene camphor (4-MBC), were analyzed in the effluent of the aerobic gray water treatment system in full operation. The effluent was used for lab-scale experiments with an electrochemical cell operated in batch mode.

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